Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | ACP3 | P15309 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 2/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4083661 | 0.88 | ACP3 (0.45) | CYP11B1CYP11B2KMT2AATMKCNN4 | |
| SCHEMBL12869580 | 0.87 | ADORA2A (0.44) | CYP11B1CYP11B2KMT2AADORA2AADORA1 | |
| SCHEMBL11862016 | 0.77 | CYP11B1 (0.39) | CYP11B1CYP11B2KMT2AATMMEN1 | |
| SCHEMBL30986699 | 0.77 | CYP11B1 (0.39) | CYP11B1CYP11B2KMT2AATMMEN1 | |
| SCHEMBL30910920 | 0.77 | CYP11B1 (0.39) | CYP11B1CYP11B2KMT2AATMMEN1 | |
| SCHEMBL30986702 | 0.76 | CES2 (0.43) | CYP11B1CYP11B2KMT2AATMKCNN4 | |
| SCHEMBL6566037 | 0.76 | CES2 (0.43) | CYP11B1CYP11B2KMT2AATMKCNN4 | |
| SCHEMBL30910940 | 0.76 | CES2 (0.43) | CYP11B1CYP11B2KMT2AATMKCNN4 | |
| SCHEMBL23003634 | 0.74 | GABRA1 (0.43) | CYP11B1CYP11B2KMT2AATMTOP2A | |
| SCHEMBL3294921 | 0.74 | ACP3 (0.57) | KMT2AADORA2AADORA1ACP3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2280983-B9 | C-ARYL GLYCOSIDE COMPOUNDS FOR THE TREATMENT OF DIABETES AND OBESITY | TFCHEM (FR) | 2021-06-09 | — | — | EP | disclosed |
| US-8486897-B2 | C-aryl glycoside compounds for the treatment of diabetes and obesity | TFCHEM (FR) | 2013-07-16 | — | — | US | disclosed |
| US-8486897-B2 | C-aryl glycoside compounds for the treatment of diabetes and obesity | TFCHEM (FR) | 2013-07-16 | — | — | US | disclosed |
| EP-2280983-B1 | C-ARYL GLYCOSIDE COMPOUNDS FOR THE TREATMENT OF DIABETES AND OBESITY | TFCHEM (FR) | 2013-03-13 | — | — | EP | disclosed |
| US-20110034402-A1 | C-ARYL GLYCOSIDE COMPOUNDS FOR THE TREATMENT OF DIABETES AND OBESITY | TFCHEM | 2011-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034402-A1 | C-ARYL GLYCOSIDE COMPOUNDS FOR THE TREATMENT OF DIABETES AND OBESITY | SLC5A2, SLC5A1, GPR119 | CYP11B1 51/4885CYP11B2 76/4885KMT2A 4088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.