SCHEMBL1287155

SCHEMBL1287155

CCCCOC(=O)NC(C(=O)O)C(C)C

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.53
PLA2G2A P14555 1/20 0.51
PLA2G5 P39877 1/20 0.51
PPARG P37231 2/20 0.51
PPARA Q07869 1/20 0.51
MAPT P10636 1/20 0.46
HSD17B10 Q99714 1/20 0.46
EPHX1 P07099 1/20 0.44
NPC1 O15118 1/20 0.44
HPGD P15428 1/20 0.44
RAB9A P51151 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
TP53 P04637 1/20 0.43
GAA P10253 1/20 0.43
ACHE P22303 6/20 0.43
NPSR1 Q6W5P4 1/20 0.43
TYR P14679 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL509967 1.00 SMN1; SMN2 (0.53) SMN1; SMN2PLA2G2APLA2G5PPARGPPARA
SCHEMBL7755148 1.00 SMN1; SMN2 (0.53) SMN1; SMN2PLA2G2APLA2G5PPARGPPARA
SCHEMBL8467616 0.95 SMN1; SMN2 (0.55) SMN1; SMN2PLA2G2APLA2G5PPARGPPARA
SCHEMBL8466581 0.95 SMN1; SMN2 (0.55) SMN1; SMN2PLA2G2APLA2G5PPARGPPARA
SCHEMBL9828390 0.95 SMN1; SMN2 (0.55) SMN1; SMN2PLA2G2APLA2G5PPARGPPARA
SCHEMBL10481485 0.94 SMN1; SMN2 (0.48) SMN1; SMN2PLA2G2APLA2G5PPARGPPARA
SCHEMBL10481483 0.94 SMN1; SMN2 (0.48) SMN1; SMN2PLA2G2APLA2G5PPARGPPARA
SCHEMBL7770760 0.93 PLA2G2A (0.56) SMN1; SMN2PLA2G2APLA2G5PPARGPPARA
SCHEMBL7770749 0.93 PLA2G2A (0.56) SMN1; SMN2PLA2G2APLA2G5PPARGPPARA
SCHEMBL7770751 0.93 PLA2G2A (0.56) SMN1; SMN2PLA2G2APLA2G5PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3429354-A1 B-VITAMIN AND AMINO ACID CONJUGATES OF NICOTINOYL RIBOSIDES AND REDUCED NICOTINOYL RIBOSIDES, DERIVATIVES THEREOF, AND METHODS OF PREPARATION THEREOF Chromadex Inc. (US) 2019-01-23 EP claimed
WO-2017161165-A1 B-VITAMIN AND AMINO ACID CONJUGATES OF NICOTINOYL RIBOSIDES AND REDUCED NICOTINOYL RIBOSIDES, DERIVATIVES THEREOF, AND METHODS OF PREPARATION THEREOF ChromaDex Inc. (US) 2017-09-21 WO claimed
CN-103333135-B Synthesis technology of benthiavalicarb isopropyl UNIV SHANGQIU NORMAL 2015-04-15 CN claimed
EP-3341007-A1 MALT1 INHIBITORS AND USES THEREOF Cornell University (US) 2018-07-04 EP disclosed
WO-2017040304-A1 MALT1 INHIBITORS AND USES THEREOF CORNELL UNIVERSITY (US) 2017-03-09 WO disclosed
CN-104910039-A Functional phenylacetylene compound and preparation method thereof UNIV HARBIN ENG 2015-09-16 CN disclosed
CN-104593173-A Detergent for grapes YANTAI SHUNLONG CHEMICAL TECHNOLOGY CO LTD 2015-05-06 CN disclosed
CN-103333135-B Synthesis technology of benthiavalicarb isopropyl UNIV SHANGQIU NORMAL 2015-04-15 CN disclosed
CN-103288833-A Imidazo triazines and imidazo pyrimidines as kinase inhibitors INCYTE CORP 2013-09-11 CN disclosed
CN-101641093-B Imidazotriazines and imidazopyrimidines as kinase inhibitors INCYTE CORP 2013-05-29 CN disclosed
WO-2012170209-A2 BENZOFURAN-2 CARBOXAMIDE COMPOUNDS NECTID, INC. (US) 2012-12-13 WO disclosed
WO-2004071454-A2 SUBSTITUTED AZETIDINE COMPOUNDS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV GUILFORD PHARMACEUTICALS INC. (US) 2004-08-26 WO disclosed
WO-2004026822-A2 PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) ABBOTT LABORATORIES (US) 2004-04-01 WO disclosed
EP-1392315-A1 METHODS OF TREATING ALZHEIMER'S DISEASE Elan Pharmaceuticals, Inc. (US) 2004-03-03 EP disclosed
WO-2002100410-A1 METHODS OF TREATING ALZHEIMER'S DISEASE ELAN PHARMACEUTICALS, INC. (US) 2002-12-19 WO disclosed
EP-1015444-A1 NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION, LTD. (KR) 2000-07-05 EP disclosed
WO-1998043968-A1 NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION (KR) 1998-10-08 WO disclosed
US-5753652-A Antiretroviral hydrazine derivatives NOVARTIS CORPORATION (US) 1998-05-19 US disclosed
EP-0665747-A4 BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE. MERCK & CO INC (US) 1995-11-15 EP disclosed
EP-0665747-A1 BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE MERCK & CO. INC. (US) 1995-08-09 EP disclosed