Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13360872 | 0.82 | POLB (0.49) | KDM4EHPGDHSD17B10POLBSMN1; SMN2 | |
| SCHEMBL23400415 | 0.79 | POLB (0.50) | KDM4EHSD17B10POLBSMN1; SMN2MEN1 | |
| SCHEMBL12770947 | 0.78 | MEN1 (0.65) | KDM4EHPGDHSD17B10POLBSMN1; SMN2 | |
| SCHEMBL8280284 | 0.76 | SMO (0.54) | KDM4EHPGDHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL19002543 | 0.76 | GAA (0.58) | KDM4EHPGDHSD17B10POLBSMN1; SMN2 | |
| SCHEMBL15478688 | 0.75 | HPGD (0.51) | KDM4EHPGDHSD17B10POLBSMN1; SMN2 | |
| SCHEMBL11836620 | 0.75 | SMN1; SMN2 (0.62) | KDM4EHPGDHSD17B10POLBSMN1; SMN2 | |
| SCHEMBL10604503 | 0.74 | RAB9A (0.64) | KDM4EHPGDHSD17B10POLBSMN1; SMN2 | |
| SCHEMBL10798333 | 0.73 | MAPT (0.65) | KDM4EHPGDPOLBSMN1; SMN2MEN1 | |
| SCHEMBL10798336 | 0.73 | MAPT (0.65) | KDM4EHPGDPOLBSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110046152-A1 | Amide Compounds, Preparation Methods and Uses Thereof | SINOCHEM CORPORATION | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046152-A1 | Amide Compounds, Preparation Methods and Uses Thereof | ACHE, MGAM, PGLS | KDM4E 371/4885HPGD 2395/4885HSD17B10 4498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.