Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | TAS2R14 | Q9NYV8 | 10/20 | 0.63 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.63 |
| ▸ | MEP1B | Q16820 | 4/20 | 0.56 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA4 | P22748 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1287273 | 0.88 | MEN1 (0.89) | MEN1KMT2APOLBTAS2R14CXCR3 | |
| SCHEMBL1287473 | 0.87 | MEN1 (0.65) | MEN1KMT2APOLBTAS2R14CXCR3 | |
| SCHEMBL1287330 | 0.84 | MEN1 (0.64) | MEN1KMT2APOLBTAS2R14CXCR3 | |
| SCHEMBL1287453 | 0.84 | CXCR3 (0.72) | MEN1KMT2APOLBTAS2R14CXCR3 | |
| SCHEMBL1287301 | 0.82 | MEN1 (1.00) | MEN1KMT2APOLBTAS2R14CXCR3 | |
| SCHEMBL1287378 | 0.82 | MEN1 (0.73) | MEN1KMT2APOLBTAS2R14CXCR3 | |
| SCHEMBL1287314 | 0.82 | MEN1 (0.77) | MEN1KMT2APOLBTAS2R14CXCR3 | |
| SCHEMBL1287293 | 0.81 | MEN1 (0.60) | MEN1KMT2APOLBTAS2R14CXCR3 | |
| SCHEMBL1287431 | 0.81 | MEN1 (0.65) | MEN1KMT2APOLBTAS2R14CXCR3 | |
| SCHEMBL1615782 | 0.80 | TAS2R14 (0.83) | MEN1KMT2ATAS2R14CXCR3MEP1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047926-A2 | SULFONAMIDE-CONTAINING COMPOUNDS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2012-04-12 | — | — | WO | disclosed |