Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | CNR2 | P34972 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | MMP7 | P09237 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | BMP1 | P13497 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1287373 | 1.00 | ALDH1A1 (0.68) | ALDH1A1POLBCNR2CYP1A2CYP3A4 | |
| Acetic Acid SCHEMBL8970513 | 0.94 | POLB (0.68) | ALDH1A1POLBCNR2CYP1A2CYP3A4 | |
| SCHEMBL31124612 | 0.91 | MMP2 (0.58) | ALDH1A1POLBCNR2MMP2CA12 | |
| SCHEMBL28426090 | 0.88 | ALDH1A1 (0.73) | ALDH1A1POLBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3759433 | 0.88 | ALDH1A1 (0.73) | ALDH1A1POLBCYP1A2CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL8123779 | 0.86 | ALDH1A1 (0.71) | ALDH1A1POLBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28423968 | 0.85 | ALDH1A1 (0.69) | ALDH1A1POLBCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14619788 | 0.85 | ALDH1A1 (0.69) | ALDH1A1POLBCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20021998 | 0.85 | ALDH1A1 (0.69) | ALDH1A1POLBMMP2CA12CA2 | |
| SCHEMBL3757552 | 0.83 | ALDH1A1 (0.68) | ALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130310384-A1 | Sulfonamide-Containing Compounds | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2013-11-21 | — | — | US | disclosed |
| WO-2012047926-A2 | SULFONAMIDE-CONTAINING COMPOUNDS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2012-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130310384-A1 | Sulfonamide-Containing Compounds | BACE1, BACE2, GSAP | ALDH1A1 3025/4885POLB 3557/4885CNR2 730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.