Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3535555 | 0.85 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2ACYP19A1PPARG | |
| SCHEMBL21569712 | 0.85 | AKR1C3 (0.45) | ALDH1A1MEN1KMT2ATP53GAA | |
| SCHEMBL9129286 | 0.80 | F2 (0.61) | ALDH1A1MEN1KMT2ATP53GAA | |
| SCHEMBL8883022 | 0.80 | NQO2 (0.61) | ALDH1A1MEN1KMT2ATP53GAA | |
| SCHEMBL21569714 | 0.79 | L3MBTL1 (0.51) | ALDH1A1KMT2AGAA | |
| SCHEMBL1021941 | 0.79 | TAAR1 (0.56) | ALDH1A1MEN1KMT2ATP53GAA | |
| SCHEMBL1287281 | 0.78 | PRMT1 (0.83) | ALDH1A1MEN1KMT2ATP53GAA | |
| SCHEMBL21569715 | 0.78 | MPO (0.41) | TBXA2RCA1CA2 | |
| SCHEMBL31277145 | 0.78 | MPO (0.41) | TBXA2RCA1CA2 | |
| SCHEMBL15717313 | 0.78 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ATP53TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047926-A2 | SULFONAMIDE-CONTAINING COMPOUNDS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2012-04-12 | — | — | WO | disclosed |