Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 14/20 | 0.72 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.65 |
| ▸ | PTGES | O14684 | 2/20 | 0.65 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.65 |
| ▸ | CNR2 | P34972 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1615462 | 0.91 | TAS2R14 (0.78) | TAS2R14CXCR3PTGESTAS2R8CNR2 | |
| SCHEMBL1169679 | 0.91 | TAS2R14 (0.78) | TAS2R14CXCR3PTGESTAS2R8CNR2 | |
| SCHEMBL1287314 | 0.89 | MEN1 (0.77) | TAS2R14CXCR3PTGESTAS2R8KMT2A | |
| SCHEMBL1287512 | 0.86 | CNR2 (0.62) | TAS2R14CXCR3PTGESTAS2R8CNR2 | |
| SCHEMBL1287503 | 0.85 | TAS2R14 (0.71) | TAS2R14CXCR3PTGESTAS2R8KMT2A | |
| SCHEMBL1278914 | 0.84 | TAS2R14 (1.00) | TAS2R14CXCR3PTGESTAS2R8KMT2A | |
| SCHEMBL1615931 | 0.84 | TAS2R14 (1.00) | TAS2R14CXCR3PTGESTAS2R8KMT2A | |
| SCHEMBL1287273 | 0.83 | MEN1 (0.89) | TAS2R14CXCR3PTGESTAS2R8CNR2 | |
| SCHEMBL1287407 | 0.83 | TAS2R14 (0.81) | TAS2R14CXCR3PTGESKMT2AMEN1 | |
| SCHEMBL1287359 | 0.83 | TAS2R14 (0.83) | TAS2R14CXCR3PTGESTAS2R8KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047926-A2 | SULFONAMIDE-CONTAINING COMPOUNDS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2012-04-12 | — | — | WO | disclosed |