Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | TACR2 | P21452 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12704406 | 1.00 | GPR35 (0.37) | GPR35ALDH1A1DNM1TYMPTSHR | |
| SCHEMBL16139815 | 0.84 | GPR35 (0.43) | GPR35TSHRALOX5TP53CYP3A4 | |
| SCHEMBL12873847 | 0.84 | GPR35 (0.35) | GPR35ALOX5PTGS2 | |
| SCHEMBL12704412 | 0.83 | GPR35 (0.54) | GPR35 | |
| SCHEMBL1157428 | 0.83 | GPR35 (0.54) | GPR35 | |
| SCHEMBL991441 | 0.82 | ALDH1A1 (0.41) | GPR35ALDH1A1TYMPTSHRTHRB | |
| SCHEMBL12874160 | 0.82 | GPR35 (0.35) | GPR35ALOX5PTGS2 | |
| SCHEMBL12709450 | 0.81 | GPR35 (0.38) | GPR35ALDH1A1DNM1TYMPTSHR | |
| SCHEMBL12017133 | 0.81 | GPR35 (0.38) | GPR35ALDH1A1DNM1TYMPTSHR | |
| SCHEMBL1157128 | 0.81 | GPR35 (0.56) | GPR35ALDH1A1ESR1ADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773646-B1 | CONJUGATED FUSED THIOPHENES, METHODS OF MAKING CONJUGATED FUSED THIOPHENES, AND USES THEREOF | CORNING INC (US) | 2016-06-15 | — | — | EP | disclosed |
| EP-1799688-B1 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | CORNING INC (US) | 2013-06-19 | — | — | EP | disclosed |
| US-8349998-B2 | Fused thiophenes, methods for making fused thiophenes, and uses thereof | CORNING INCORPORATED (US) | 2013-01-08 | — | — | US | disclosed |
| US-7893191-B2 | Fused thiophenes, methods for making fused thiophenes, and uses thereof | CORNING INCORPORATED (US) | 2011-02-22 | — | — | US | disclosed |
| US-20110040042-A1 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | HE MINGQIAN | 2011-02-17 | — | — | US | disclosed |
| US-7705108-B2 | Fused thiophenes, methods for making fused thiophenes, and uses thereof | CORNING INCORPORATED (US) | 2010-04-27 | — | — | US | disclosed |
| US-20100010237-A1 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | HE MINGQIAN | 2010-01-14 | — | — | US | disclosed |
| US-20070265418-A1 | Fused Thiophenes, Methods for Making Fused Thiophenes, and Uses Thereof | CORNING INCORPORATED | 2007-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110040042-A1 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | TPMT, TST, TYMP | GPR35 4429/4885ALDH1A1 2135/4885DNM1 1780/4885 |
| US-20100010237-A1 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | TPMT, TST, TYMP | GPR35 4520/4885ALDH1A1 2157/4885DNM1 1856/4885 |
| US-20070265418-A1 | Fused Thiophenes, Methods for Making Fused Thiophenes, and Uses Thereof | TPMT, TST, TYMP | GPR35 4429/4885ALDH1A1 2135/4885DNM1 1780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.