Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 15/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1169453 | 0.86 | CXCR3 (1.00) | CXCR3MEN1KMT2APOLBTAS2R14 | |
| SCHEMBL1287461 | 0.83 | MEN1 (0.60) | CXCR3MEN1KMT2APOLBTAS2R14 | |
| SCHEMBL1287435 | 0.82 | MEN1 (0.66) | CXCR3MEN1KMT2APOLBTAS2R14 | |
| SCHEMBL1287468 | 0.81 | MEN1 (0.64) | CXCR3MEN1KMT2APOLBTAS2R14 | |
| SCHEMBL1287336 | 0.79 | MEN1 (0.62) | CXCR3MEN1KMT2APOLBTAS2R14 | |
| SCHEMBL1287403 | 0.79 | MEN1 (0.62) | CXCR3MEN1KMT2APOLBTAS2R14 | |
| SCHEMBL1169626 | 0.79 | CXCR3 (1.00) | CXCR3MEN1KMT2ATAS2R14 | |
| SCHEMBL1287273 | 0.79 | MEN1 (0.89) | CXCR3MEN1KMT2APOLBTAS2R14 | |
| SCHEMBL1673402 | 0.79 | CXCR3 (0.61) | CXCR3POLBKDM4ELMNAHTT | |
| SCHEMBL15388269 | 0.79 | CXCR3 (0.61) | CXCR3POLBKDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047926-A2 | SULFONAMIDE-CONTAINING COMPOUNDS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2012-04-12 | — | — | WO | disclosed |