Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9907645 | 0.82 | HTR5A (0.62) | HTR5AALDH1A1L3MBTL1GRM2TP53 | |
| SCHEMBL15500548 | 0.81 | HTR5A (0.55) | HTR5AALDH1A1L3MBTL1GRM2TP53 | |
| SCHEMBL9907332 | 0.79 | HTR5A (0.64) | HTR5AALDH1A1L3MBTL1CYP1A2NPC1 | |
| SCHEMBL9907903 | 0.76 | HTR5A (0.86) | HTR5AGRM2 | |
| SCHEMBL9907649 | 0.76 | HTR5A (0.54) | HTR5AALDH1A1L3MBTL1CYP1A2NPC1 | |
| SCHEMBL12874519 | 0.75 | ALDH1A1 (0.43) | HTR5AALDH1A1L3MBTL1CYP1A2NPC1 | |
| SCHEMBL9907336 | 0.75 | ALDH1A1 (0.50) | HTR5AALDH1A1L3MBTL1CYP1A2NPC1 | |
| SCHEMBL12875021 | 0.75 | ALDH1A1 (0.43) | HTR5AALDH1A1L3MBTL1CYP1A2NPC1 | |
| SCHEMBL15500532 | 0.74 | HTR5A (0.41) | HTR5AALDH1A1L3MBTL1CYP1A2NPC1 | |
| SCHEMBL9907333 | 0.74 | HTR5A (0.72) | HTR5AALDH1A1L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011016504-A1 | NITROGENOUS-RING ACYLGUANIDINE DERIVATIVE | アステラス製薬株式会社 (JP) | 2011-02-10 | — | — | WO | disclosed |