Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 14/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12875043 | 0.93 | HTR5A (0.45) | HTR5APTGDR2MAPK14 | |
| SCHEMBL9907847 | 0.90 | HTR5A (0.52) | HTR5A | |
| SCHEMBL9925362 | 0.87 | HTR5A (0.38) | HTR5APTGDR2 | |
| SCHEMBL12875077 | 0.86 | HTR5A (0.45) | HTR5APTGDR2MAPK14 | |
| SCHEMBL12874645 | 0.85 | HTR5A (0.38) | HTR5AMAPK14 | |
| SCHEMBL9925360 | 0.85 | MAPK14 (0.41) | HTR5AMAPK14 | |
| SCHEMBL9925361 | 0.85 | HTR5A (0.42) | HTR5APTGDR2 | |
| SCHEMBL12874646 | 0.83 | GRM2 (0.36) | HTR5AMAPK14GRM2 | |
| SCHEMBL9907821 | 0.82 | HTR5A (0.56) | HTR5AMAPK14 | |
| SCHEMBL9907486 | 0.81 | PTGDR2 (0.38) | HTR5APTGDR2MAPK14GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011016504-A1 | NITROGENOUS-RING ACYLGUANIDINE DERIVATIVE | アステラス製薬株式会社 (JP) | 2011-02-10 | — | — | WO | disclosed |