Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 1/20 | 0.71 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SGMS1 | Q86VZ5 | 3/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4618234 | 0.89 | TBXA2R (0.58) | TBXA2RTBXAS1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL1287477 | 0.86 | ALDH1A1 (0.68) | TBXA2RTBXAS1ALDH1A1POLBCA1 | |
| SCHEMBL11379516 | 0.85 | TBXA2R (0.74) | TBXA2RTBXAS1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL4618078 | 0.84 | SFRP1 (0.77) | TBXA2RTBXAS1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL9130476 | 0.83 | TBXA2R (0.68) | TBXA2RTBXAS1ALDH1A1POLBSMN1; SMN2 | |
| Sulotroban SCHEMBL34187 | 0.83 | TBXA2R (1.00) | TBXA2RTBXAS1ALDH1A1POLBCA1 | |
| SCHEMBL10460354 | 0.83 | ALDH1A1 (0.70) | TBXA2RTBXAS1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL11361871 | 0.81 | TBXA2R (0.72) | TBXA2RTBXAS1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL11332922 | 0.81 | TBXA2R (0.81) | TBXA2RTBXAS1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL9127040 | 0.81 | TBXA2R (0.81) | TBXA2RTBXAS1ALDH1A1POLBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011057262-A2 | TREATMENT OF INFECTIONS WITH TP RECEPTOR ANTAGONISTS | EVOLVA INC. (US) | 2011-05-12 | — | — | WO | disclosed |