SCHEMBL1287534

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11843232	0.88	EYA3 (0.77)	CYP2C19EYA3TTRCYP2C9MEN1
	SCHEMBL1287955	0.87	EYA3 (0.68)	CYP2C19EYA3TTRCYP2C9MEN1
	SCHEMBL1287573	0.85	CYP2C19 (1.00)	CYP2C19EYA3TTRCYP2C9MEN1
	Benziodarone SCHEMBL31326233	0.85	EYA3 (1.00)	CYP2C19EYA3TTRCYP2C9MEN1
	Benziodarone SCHEMBL308541	0.85	EYA3 (1.00)	CYP2C19EYA3TTRCYP2C9MEN1
	Benzbromarone SCHEMBL48993	0.84	SLC22A12 (1.00)	CYP2C19EYA3TTRCYP2C9MEN1
	SCHEMBL18629878	0.84	CYP2C19 (0.74)	CYP2C19EYA3TTRCYP2C9MEN1
	Benzbromarone SCHEMBL19205474	0.84	SLC22A12 (1.00)	CYP2C19EYA3TTRCYP2C9MEN1
	Benzbromarone SCHEMBL29361528	0.84	SLC22A12 (1.00)	CYP2C19EYA3TTRCYP2C9MEN1
	SCHEMBL27935343	0.83	EYA3 (0.77)	CYP2C19EYA3TTRCYP2C9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.