Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 2/20 | 0.42 |
| ▸ | DCTPP1 | Q9H773 | 4/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12875714 | 0.92 | LIPE (0.42) | LIPECNR1CNR2 | |
| SCHEMBL12875711 | 0.89 | LIPE (0.43) | LIPEDCTPP1HDAC3HDAC1HDAC2 | |
| SCHEMBL12875143 | 0.81 | CNR2 (0.49) | LIPEDCTPP1HDAC3HDAC1HDAC2 | |
| SCHEMBL12875144 | 0.80 | LIPE (0.43) | LIPECNR1CNR2 | |
| SCHEMBL1147348 | 0.78 | LIPE (0.45) | LIPEEPHX2MAPT | |
| SCHEMBL12875690 | 0.73 | CHRNB2 (0.50) | LIPECNR1CNR2MAPT | |
| SCHEMBL15387585 | 0.72 | LIPE (0.43) | LIPEHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL1146713 | 0.69 | LIPE (0.45) | LIPECNR2MAPT | |
| SCHEMBL1147336 | 0.68 | LIPE (0.46) | LIPEEPHX2CCR1CNR2 | |
| SCHEMBL11888889 | 0.66 | HDAC1 (0.49) | DCTPP1HDAC3HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011012602-A1 | PIPERIDINE DERIVATIVES AND THEIR USE TO TREAT OBESITY, DIABETES, DYSLIPIDEMIA AND ATHEROSCLEROSIS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-02-03 | — | — | WO | disclosed |