Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.68 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.68 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.55 |
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | NNMT | P40261 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.50 |
| ▸ | OXTR | P30559 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | TTK | P33981 | 1/20 | 0.47 |
| ▸ | CLK2 | P49760 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14516103 | 0.87 | NNMT (0.64) | MKNK1MKNK2PLK1NNMTHDAC6 | |
| SCHEMBL27873385 | 0.86 | MKNK1 (0.70) | MKNK1MKNK2CD274NNMTHDAC6 | |
| SCHEMBL2225323 | 0.86 | KCNH2 (0.63) | MKNK1MKNK2 | |
| SCHEMBL13702343 | 0.84 | MEN1 (0.63) | MKNK1MKNK2HDAC6HDAC3HSD17B1 | |
| SCHEMBL2945799 | 0.84 | MKNK1 (0.71) | MKNK1MKNK2CD274NNMTHDAC6 | |
| SCHEMBL30280631 | 0.82 | MKNK1 (0.73) | MKNK1MKNK2CD274NNMTHDAC6 | |
| SCHEMBL29365356 | 0.82 | MKNK1 (0.73) | MKNK1MKNK2CD274NNMTHDAC6 | |
| SCHEMBL1870306 | 0.82 | MKNK1 (0.73) | MKNK1MKNK2CD274NNMTHDAC6 | |
| SCHEMBL12641872 | 0.82 | MKNK1 (0.73) | MKNK1MKNK2CD274NNMTHDAC6 | |
| SCHEMBL12582087 | 0.78 | MKNK1 (0.68) | MKNK1MKNK2CD274NNMTHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011017564-A2 | IDENTIFICATION AND USE OF COMPOUNDS FOR TREATING PERSISTENT PAIN | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2011-02-10 | — | — | WO | disclosed |