Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CDK8 | P49336 | 7/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8795679 | 0.81 | AR (0.45) | ARSMN1; SMN2TDP1MEN1KMT2A | |
| SCHEMBL10066804 | 0.80 | AR (0.44) | ARSMN1; SMN2TDP1MEN1KMT2A | |
| SCHEMBL15787042 | 0.79 | AR (0.42) | ARSMN1; SMN2TDP1MEN1KMT2A | |
| SCHEMBL15787043 | 0.79 | AR (0.42) | ARSMN1; SMN2TDP1MEN1KMT2A | |
| SCHEMBL8795382 | 0.79 | AR (0.42) | ARSMN1; SMN2TDP1MEN1KMT2A | |
| SCHEMBL27512257 | 0.77 | AR (0.55) | ARSMN1; SMN2TDP1MEN1KMT2A | |
| SCHEMBL14340625 | 0.74 | PPARG (0.55) | ARSMN1; SMN2TDP1KMT2ALMNA | |
| SCHEMBL11234294 | 0.74 | CYP1A2 (0.56) | ARSMN1; SMN2 | |
| SCHEMBL27747165 | 0.74 | CPB2 (0.47) | CPB2SMN1; SMN2TDP1MEN1KMT2A | |
| SCHEMBL13075015 | 0.73 | MCHR1 (0.45) | CPB2SMN1; SMN2GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011016470-A1 | SULFONE DERIVATIVE | 第一三共株式会社 (JP) | 2011-02-10 | — | — | WO | disclosed |