SCHEMBL13075015

SCHEMBL13075015

CCC(C)Oc1ccc(N)nc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 2/20 0.45
NOS3 P29474 1/20 0.39
NOS2 P35228 1/20 0.39
MPO P05164 1/20 0.39
TPO P07202 1/20 0.39
EPX P11678 1/20 0.39
LPO P22079 1/20 0.39
CDK1 P06493 1/20 0.37
CCNB1 P14635 1/20 0.37
CCNA2 P20248 1/20 0.37
CDK2 P24941 1/20 0.37
CCNA1 P78396 1/20 0.37
LTA4H P09960 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
NPC1 O15118 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
RAB9A P51151 1/20 0.36
GPBAR1 Q8TDU6 1/20 0.36
CYSLTR1 Q9Y271 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1000603 0.83 NOS3 (0.46) MCHR1NOS3NOS2MPOTPO
SCHEMBL18291374 0.81 MCHR1 (0.38) MCHR1NOS3NOS2MPOTPO
Hydrochloric Acid SCHEMBL710140 0.81 NOS3 (0.45) MCHR1NOS3NOS2MPOTPO
SCHEMBL25399464 0.80 MPO (0.36) MCHR1NOS3NOS2MPOTPO
SCHEMBL25399467 0.80 MPO (0.36) MCHR1NOS3NOS2MPOTPO
SCHEMBL12923995 0.79 CHRNB2 (0.39) GPBAR1CYSLTR1ACACBGABRPGABRD
SCHEMBL122883 0.76 ACACB (0.45) MCHR1LTA4HMAPTGPBAR1CYSLTR1
SCHEMBL360929 0.75 TDP1 (0.56) NOS3NOS2MPOTPOEPX
SCHEMBL6371042 0.75 TDP1 (0.50) MCHR1SMN1; SMN2NPC1ALDH1A1MAPT
SCHEMBL746308 0.75 TDP1 (0.50) MCHR1SMN1; SMN2NPC1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010135360-A1 ISOXAZOLINES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE INFINITY PHARMACEUTICALS, INC. (US) 2010-11-25 WO disclosed