SCHEMBL128781

SCHEMBL128781

COc1ccc(O)c(C(=O)O)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.61
CA2 P00918 2/20 0.61
PTGS2 P35354 2/20 0.61
CA12 O43570 1/20 0.61
ALOX5 P09917 1/20 0.61
CA7 P43166 1/20 0.61
CA9 Q16790 1/20 0.61
CA14 Q9ULX7 1/20 0.61
SMN1; SMN2 Q16637 3/20 0.61
HPGD P15428 5/20 0.59
KDM4E B2RXH2 5/20 0.59
NPC1 O15118 4/20 0.59
RAB9A P51151 4/20 0.59
ALDH1A1 P00352 4/20 0.59
MEN1 O00255 4/20 0.59
KMT2A Q03164 4/20 0.59
LMNA P02545 3/20 0.59
HSD17B10 Q99714 3/20 0.59
TP53 P04637 2/20 0.59
MAPT P10636 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29431885 1.00 CA1 (0.61) CA1CA2PTGS2CA12ALOX5
SCHEMBL865333 0.98 SMN1; SMN2 (0.59) CA1CA2PTGS2CA12ALOX5
SCHEMBL742830 0.90 SMN1; SMN2 (0.51) CA1CA2PTGS2CA12ALOX5
SCHEMBL9148934 0.87 RAB9A (0.56) CA1CA2PTGS2CA12ALOX5
SCHEMBL28093168 0.86 RAB9A (0.71) SMN1; SMN2HPGDKDM4ENPC1RAB9A
SCHEMBL5885105 0.85 MCL1 (0.67) SMN1; SMN2MEN1KMT2ATHRBRECQL
SCHEMBL9305720 0.85 NPC1 (0.52) SMN1; SMN2HPGDKDM4ENPC1RAB9A
SCHEMBL11754309 0.85 LMNA (0.65) SMN1; SMN2HPGDKDM4ENPC1RAB9A
Butylamine SCHEMBL6519325 0.84 MCL1 (0.52) CA1CA2PTGS2CA12ALOX5
4-Methoxysalicylic Acid SCHEMBL483346 0.84 NPC1 (0.75) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4980 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122011393-A Vinyl silicone oil and preparation method thereof 江西科睿新材料有限公司 2026-05-12 CN claimed
US-20260002924-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2026-01-01 US claimed
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
US-20250214921-A1 METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND KAO CORPORATION (JP) 2025-07-03 US claimed
CN-118880486-B Cool polyester fiber and preparation method thereof 江苏恒科新材料有限公司 2025-06-24 CN claimed
CN-120058777-A Preparation method and application of tris (2-methyl-2-phenylpropyl) tin-5-methoxy salicylate complex 衡阳师范学院 2025-05-30 CN claimed
CN-119465669-A Dyeing liquid for optical resin, dyed optical resin, and preparation method and application of dyed optical resin 拓烯科技(衢州)有限公司 2025-02-18 CN claimed
EP-4501896-A1 METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND Kao Corporation (JP) 2025-02-05 EP claimed
CN-119194880-A Dyeing assistant composition for optical resin dyeing, dyeing method of optical resin and dyed optical resin 拓烯科技(衢州)有限公司 2024-12-27 CN claimed
EP-4477693-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS Korea Research Institute of Chemical Technology (KR) 2024-12-18 EP claimed
EP-0225189-A2 Targeted enteral delivery system R.P. SCHERER CORPORATION (US) 1987-06-10 EP claimed
EP-0036145-B1 AN ORALLY ADMINISTERED DRUG FORM COMPRISING A POLAR BIOACTIVE AGENT AND AN ADJUVANT INTERx RESEARCH CORPORATION (US) 1985-05-29 EP claimed
EP-0031561-B1 A RECTALLY ADMINISTERED SUPPOSITORY COMPRISING A DRUG AND AN ADJUVANT MERCK & CO. INC. (US) 1985-04-10 EP claimed
US-4470980-A Method of increasing oral absorption of β-lactam antibiotics INTERX RESEARCH CORP. (US) 1984-09-11 US claimed
US-4464363-A HYDROXY ARYL- OR HYDROXY ARALKYL ACIDS OR SALTS MERCK & CO., INC. (US) 1984-08-07 US claimed
US-4406896-A ANTIBIOTICS, ACIDS, HYDROXY MERCK & CO., INC. (US) 1983-09-27 US claimed
EP-0036534-A1 An orally administrable drug form comprising a beta-lactam antibiotic and an adjuvant INTERx RESEARCH CORPORATION (US) 1981-09-30 EP claimed
EP-0036145-A1 An orally administered drug form comprising a polar bioactive agent and an adjuvant INTERx RESEARCH CORPORATION (US) 1981-09-23 EP claimed
EP-0035770-A2 An orally administered drug form comprising a glycosidic antibiotic and an adjuvant INTERx RESEARCH CORPORATION (US) 1981-09-16 EP claimed
EP-0031561-A2 A rectally administered suppository comprising a drug and an adjuvant MERCK & CO. INC. (US) 1981-07-08 EP claimed