SCHEMBL12879

SCHEMBL12879

Cc1cccc(N(C)C)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
TSHR P16473 3/20 0.56
ACHE P22303 4/20 0.55
TDP1 Q9NUW8 2/20 0.53
MEN1 O00255 1/20 0.53
NPC1 O15118 1/20 0.53
NSD2 O96028 1/20 0.53
CASP3 P42574 1/20 0.53
RAB9A P51151 1/20 0.53
KMT2A Q03164 1/20 0.53
SENP8 Q96LD8 1/20 0.53
SENP7 Q9BQF6 1/20 0.53
SENP6 Q9GZR1 1/20 0.53
SIGMAR1 Q99720 1/20 0.47
HSD17B1 P14061 3/20 0.44
HSD17B2 P37059 3/20 0.44
MAPK1 P28482 2/20 0.44
ALOX15 P16050 1/20 0.43
HSD17B10 Q99714 1/20 0.43
EGFR P00533 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29381010 1.00 ALDH1A1 (0.56) ALDH1A1TSHRACHETDP1MEN1
SCHEMBL21065746 0.97 ALDH1A1 (0.54) ALDH1A1TSHRACHETDP1MEN1
Lithium Ion SCHEMBL19732618 0.97 ALDH1A1 (0.54) ALDH1A1TSHRACHETDP1MEN1
Hydrochloric Acid SCHEMBL2869751 0.97 ALDH1A1 (0.54) ALDH1A1TSHRACHETDP1MEN1
Nitrogen SCHEMBL11398968 0.95 ALDH1A1 (0.52) ALDH1A1TSHRACHETDP1MEN1
Toluene SCHEMBL27636807 0.93 TSHR (0.50) ALDH1A1TSHRACHETDP1MEN1
SCHEMBL24061021 0.86 HSD17B1 (0.51) ALDH1A1TSHRACHETDP1MEN1
SCHEMBL1697445 0.84 ACHE (0.55) ALDH1A1TSHRACHETDP1MEN1
SCHEMBL5884667 0.84 HSD17B1 (0.43) ALDH1A1TSHRACHETDP1MEN1
SCHEMBL4391221 0.83 ALDH1A1 (0.67) ALDH1A1TSHRACHETDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2516 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117980359-A Anaerobically curable compositions 汉高股份有限及两合公司 2024-05-03 CN claimed
CN-117416933-A Method for preparing hydroxylamine aqueous solution by hydroxylamine salt neutralization method 浙江锦华新材料股份有限公司 2024-01-19 CN claimed
US-20230278958-A1 TRICYCLIC HETEROCYCLES MERCK PATENT GMBH (DE) 2023-09-07 US claimed
CN-116640399-A (methyl) acrylic ester liquid material and preparation method and application thereof 道生天合材料科技(上海)股份有限公司 2023-08-25 CN claimed
CN-116574431-A Preparation method of corrosion-resistant cured coating for stone surface 吾尚良品环境服务(上海)有限公司 2023-08-11 CN claimed
CN-116410100-A Polymerizable cationic surfactant, hydrophobically associating polyacrylamide and preparation method 中国石油天然气股份有限公司 2023-07-11 CN claimed
US-20230174538-A1 Tricyclic heterocycles MERCK PATENT GMBH (DE) 2023-06-08 US claimed
EP-4185564-A1 TRICYCLIC HETEROCYCLES Merck Patent GmbH (DE) 2023-05-31 EP claimed
WO-2023078813-A1 HETEROBIFUNCTIONAL MOLECULES AS TEAD INHIBITORS MERCK PATENT GMBH (DE) 2023-05-11 WO claimed
CN-113004162-B Preparation method of asymmetric gem diaryl acetate compound 苏州大学 2023-05-05 CN claimed
US-4585895-A Processes for the preparation of mixed squaraine compositions XEROX CORPORATION (US) 1986-04-29 US claimed
US-4525592-A Process for squaraine compositions XEROX CORPORATION (US) 1985-06-25 US claimed
US-4524219-A REACTING AN ALKYL AQUARATE WITH AN N,N-DIALKYLANILINE IN THE PRESENCE OF AN ALKANOL XEROX CORPORATION (US) 1985-06-18 US claimed
US-4524218-A FROM SQUARIC ACID AN AROMATIC AMINE, AND A PHENOL OR PHENOL SWUARINE XEROX CORPORATION (US) 1985-06-18 US claimed
US-4506075-A PYRIDINE, BENZOYL CHLORIDE, 3-METHYL-N,N-DIALKYLBENZENEAMINE, COPPER STERLING DRUG INC. (US) 1985-03-19 US claimed
US-4487752-A OXIDATION AMMONIUM IODIDE IN PRESENCE OF TRANSITION METAL COMPOUND AND WEAK ACID ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1984-12-11 US claimed
EP-0101282-A1 A method for producing iodine or iodine derivatives Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1984-02-22 EP claimed
US-4397931-A Stabilized organic layered photoconductive device XEROX CORPORATION (US) 1983-08-09 US claimed
US-4251629-A COLORIMETRY, USING 4-AMINOANTIPYRENE, N-SUBSTITUTED ANILINE, ACTIVATOR WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1981-02-17 US claimed
US-4005055-A Anaerobic aminimide curing compositions SKEIST LABORATORIES, INCORPORATED (US) 1977-01-25 US claimed