Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TK1 | P04183 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1287942 | 0.87 | ALDH1A1 (0.52) | ALDH1A1TK1DAOUPP1MAPK1 | |
| SCHEMBL1287949 | 0.78 | HTT (0.36) | UPP1KDM4EMAPK1 | |
| SCHEMBL7540000 | 0.76 | TK1 (0.46) | ALDH1A1TK1DAOUPP1MAPT | |
| SCHEMBL20870268 | 0.74 | GRIA1 (0.38) | ALDH1A1CYP2C9KDM4EMAPTMAPK1 | |
| SCHEMBL9016400 | 0.74 | UPP1 (0.53) | UPP1 | |
| SCHEMBL13384426 | 0.74 | UPP1 (0.39) | CYP2C9UPP1MAPT | |
| SCHEMBL1287911 | 0.73 | ALDH1A1 (0.44) | ALDH1A1DAOL3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL6719842 | 0.71 | ALDH1A1 (0.52) | ALDH1A1TK1DAOCYP2C9CYP2C19 | |
| SCHEMBL13384443 | 0.71 | SMN1; SMN2 (0.40) | CYP2C9CYP2C19KDM4EMAPTMAPK1 | |
| SCHEMBL13384415 | 0.70 | HPGD (0.66) | TK1DAOMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047993-A2 | N-HYDROXYPYRIMIDINE-2,4-DIONES AS INHIBITORS OF HIV AND HCV | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2012-04-12 | — | — | WO | disclosed |