Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1287942 | 0.88 | ALDH1A1 (0.52) | TK1ALDH1A1HPGDUPP1DAO | |
| SCHEMBL7541951 | 0.82 | UPP1 (0.46) | TK1ALDH1A1HPGDUPP1DAO | |
| SCHEMBL7535480 | 0.81 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL1287902 | 0.76 | ALDH1A1 (0.39) | TK1ALDH1A1UPP1DAOMAPT | |
| SCHEMBL13384415 | 0.74 | HPGD (0.66) | TK1HPGDDAO | |
| SCHEMBL127842 | 0.73 | ALDH1A1 (0.40) | TK1ALDH1A1HPGDUPP1MAPT | |
| SCHEMBL6722443 | 0.70 | HPGD (0.68) | TK1ALDH1A1HPGDUPP1 | |
| SCHEMBL8426874 | 0.70 | ALDH1A1 (0.46) | TK1ALDH1A1HPGDDAOMAPT | |
| SCHEMBL1288013 | 0.69 | UPP1 (0.59) | TK1ALDH1A1HPGDUPP1DAO | |
| SCHEMBL1287949 | 0.68 | HTT (0.36) | UPP1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748316-B1 | PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES | SUNKYONG IND LTD (KR) | 2002-05-08 | — | — | EP | disclosed |
| US-5889013-A | REACTING AN URACIL COMPOUND WITH N, O-BIS/TRIMETHYLSILYL/ACETAMIDE FOLLOWED BY TETRABUTYLAMMONIUM IODIDE AND CHLOROMETHYL ETHER COMPOUND AND THEN REACTING WITH ARYL SELENOL IN A BASE | SUNKYONG INDUSTRIES CO., INC. (KR) | 1999-03-30 | — | — | US | disclosed |
| EP-0748316-A1 | PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES | SUNKYONG INDUSTRIES CO., LTD. (KR) | 1996-12-18 | — | — | EP | disclosed |
| WO-1995023138-A1 | PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES | SUNKYONG INDUSTRIES CO., LTD. (KR) | 1995-08-31 | — | — | WO | disclosed |