Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 2/20 | 0.36 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL598947 | 0.89 | ALDH1A1 (0.45) | KMT2ATSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2107018 | 0.81 | SMN1; SMN2 (0.36) | KMT2ADAOSMN1; SMN2ALDH1A1 | |
| SCHEMBL5200095 | 0.77 | UPP1 (0.60) | ALDH1A1 | |
| SCHEMBL1687635 | 0.77 | ALDH1A1 (0.46) | KMT2ATSHRDAOHTTCYP1A2 | |
| SCHEMBL1287911 | 0.74 | ALDH1A1 (0.44) | KMT2ATSHRDAOBRDTHTT | |
| SCHEMBL5199373 | 0.74 | UPP1 (0.45) | KMT2ATSHRDAOALDH1A1L3MBTL1 | |
| SCHEMBL27691588 | 0.73 | ALDH1A1 (0.45) | KMT2ATSHRDAOCYP3A4CYP2C9 | |
| SCHEMBL27711771 | 0.73 | ALDH1A1 (0.57) | KMT2ATSHRDAOCYP3A4CYP2C9 | |
| SCHEMBL27711721 | 0.72 | ALDH1A1 (0.52) | KMT2ATSHRDAOGAACYP3A4 | |
| SCHEMBL1287928 | 0.72 | ALDH1A1 (0.53) | CYP2C9CYP2C19SMN1; SMN2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047993-A2 | N-HYDROXYPYRIMIDINE-2,4-DIONES AS INHIBITORS OF HIV AND HCV | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2012-04-12 | — | — | WO | disclosed |