Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UPP1 | Q16831 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PNP | P00491 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL598947 | 0.88 | ALDH1A1 (0.45) | UPP1ALDH1A1HPGD | |
| SCHEMBL5199373 | 0.86 | UPP1 (0.45) | UPP1ALDH1A1HPGD | |
| SCHEMBL5199239 | 0.86 | UPP1 (0.44) | UPP1PNP | |
| SCHEMBL7219933 | 0.85 | UPP1 (0.59) | UPP1ALDH1A1HPGDPNP | |
| SCHEMBL5198534 | 0.80 | UPP1 (0.38) | UPP1ALDH1A1 | |
| SCHEMBL8760090 | 0.79 | UPP1 (0.49) | UPP1ALDH1A1 | |
| SCHEMBL8429654 | 0.79 | UPP1 (0.49) | UPP1ALDH1A1HPGD | |
| SCHEMBL5199124 | 0.79 | UPP1 (0.37) | UPP1 | |
| SCHEMBL8760096 | 0.78 | UPP1 (0.48) | UPP1ALDH1A1 | |
| SCHEMBL1287950 | 0.77 | KMT2A (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449726-B1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | MITSUBISHI CHEM CORP (JP) | 1997-06-11 | — | — | EP | claimed |
| US-5318972-A | Active against retroviruses, human t-cell leukemia/lymphoma viruses | MITSUBISHI KASEI CORPORATION (JP) | 1994-06-07 | — | — | US | claimed |
| EP-0449726-A1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | Mitsubishi Chemical Corporation (JP) | 1991-10-02 | — | — | EP | claimed |
| EP-1355887-B1 | PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES, PREPARATION METHOD AND USE THEREOF | UNIV GENEVE (CH) | 2007-08-15 | — | — | EP | disclosed |
| US-6911450-B1 | Pyrimidine acyclonucleoside derivatives, preparation method and use thereof | UNIVERSITE DE GENEVE (CH) | 2005-06-28 | — | — | US | disclosed |
| EP-1355887-A1 | PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES, PREPARATION METHOD AND USE THEREOF | UNIVERSITE DE GENEVE (CH) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002060880-A1 | PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES, PREPARATION METHOD AND USE THEREOF | UNIVERSITE DE GENEVE (CH) | 2002-08-08 | — | — | WO | disclosed |
| EP-0449726-B1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | MITSUBISHI CHEM CORP (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5318972-A | Active against retroviruses, human t-cell leukemia/lymphoma viruses | MITSUBISHI KASEI CORPORATION (JP) | 1994-06-07 | — | — | US | disclosed |
| EP-0449726-A1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | Mitsubishi Chemical Corporation (JP) | 1991-10-02 | — | — | EP | disclosed |