Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14528777 | 0.89 | CYP1A2 (0.36) | ALDH1A1CYP1A2CYP2C19CYP2C9HSD17B10 | |
| SCHEMBL4647920 | 0.79 | ALDH1A1 (0.44) | ALDH1A1CYP1A2CYP2C19CYP2C9HSD17B10 | |
| SCHEMBL4642610 | 0.77 | ALDH1A1 (0.42) | ALDH1A1CYP1A2CYP2C19CYP2C9HSD17B10 | |
| SCHEMBL29853842 | 0.77 | ALDH1A1 (0.42) | ALDH1A1CYP1A2CYP2C19CYP2C9HSD17B10 | |
| SCHEMBL12880578 | 0.74 | L3MBTL1 (0.43) | ALDH1A1CYP1A2CYP2C19HSD17B10HIF1A | |
| SCHEMBL23527410 | 0.71 | MEN1 (0.43) | ALDH1A1CYP1A2CYP2C19HSD17B10HIF1A | |
| SCHEMBL40806 | 0.70 | ALDH1A1 (0.44) | ALDH1A1CYP1A2CYP2C19HSD17B10HIF1A | |
| SCHEMBL488964 | 0.70 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP2C19HSD17B10HIF1A | |
| SCHEMBL23391018 | 0.70 | ALDH1A1 (0.44) | ALDH1A1CYP1A2CYP2C19HSD17B10HIF1A | |
| SCHEMBL4644163 | 0.70 | ALDH1A1 (0.44) | ALDH1A1CYP1A2CYP2C19HSD17B10HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7884175-B2 | polymerizing one or more monomers containing dihalogen containing substituted biaryls, via a base-induced dehydrohalogenation | MERCK PATENT GMBH (DE) | 2011-02-08 | — | — | US | disclosed |
| US-7884175-B2 | polymerizing one or more monomers containing dihalogen containing substituted biaryls, via a base-induced dehydrohalogenation | MERCK PATENT GMBH (DE) | 2011-02-08 | — | — | US | disclosed |
| EP-1623471-B1 | METHOD FOR CONTROLLING THE MOLECULAR WEIGHT DURING POLY(ARYLENE VINYLENE) SYNTHESIS, AND POLYMERS PRODUCED THEREWITH | MERCK PATENT GMBH (DE) | 2007-05-30 | — | — | EP | disclosed |