Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL240650 | 0.81 | UGT2B7 (0.47) | ALDH1A1CYP1A2HSD17B10MEN1KMT2A | |
| SCHEMBL13180821 | 0.81 | HTR2A (0.45) | ALDH1A1CYP1A2HSD17B10MEN1KMT2A | |
| SCHEMBL27994398 | 0.81 | ALDH1A1 (0.43) | ALDH1A1CYP1A2HSD17B10MEN1KMT2A | |
| SCHEMBL7560523 | 0.81 | UGT2B7 (0.47) | ALDH1A1CYP1A2HSD17B10MEN1KMT2A | |
| SCHEMBL9051490 | 0.78 | LMNA (0.49) | ALDH1A1CYP1A2HSD17B10MEN1KMT2A | |
| SCHEMBL2482183 | 0.76 | ALDH1A1 (0.39) | ALDH1A1CYP1A2HSD17B10MEN1KMT2A | |
| SCHEMBL977301 | 0.76 | ALDH1A1 (0.39) | ALDH1A1CYP1A2HSD17B10MEN1KMT2A | |
| SCHEMBL6394971 | 0.76 | KMT2A (0.53) | ALDH1A1CYP1A2HSD17B10MEN1KMT2A | |
| SCHEMBL243405 | 0.76 | LMNA (0.47) | ALDH1A1CYP1A2HSD17B10MEN1KMT2A | |
| SCHEMBL3075110 | 0.76 | ALDH1A1 (0.39) | ALDH1A1CYP1A2HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8105836-B2 | Chemical inhibitors of mismatch repair | MORPHOTEK, INC. (US) | 2012-01-31 | — | — | US | claimed |
| EP-1351565-B1 | CHEMICAL INHIBITORS OF MISMATCH REPAIR | MORPHOTEK INC (US) | 2011-03-16 | — | — | EP | claimed |
| US-6982169-B2 | Chemical inhibitors of mismatch repair | MORPHOTEK, INC. (US) | 2006-01-03 | — | — | US | claimed |
| EP-1351565-A4 | CHEMICAL INHIBITORS OF MISMATCH REPAIR | MORPHOTEK INC (US) | 2005-05-25 | — | — | EP | claimed |
| EP-1417329-A4 | METHODS FOR GENERATING ANTIBIOTIC RESISTANT MICROBES AND NOVEL ANTIBIOTICS | MORPHOTEK INC (US) | 2005-05-11 | — | — | EP | claimed |
| EP-1417329-A1 | METHODS FOR GENERATING ANTIBIOTIC RESISTANT MICROBES AND NOVEL ANTIBIOTICS | Morphotek Inc. (US) | 2004-05-12 | — | — | EP | claimed |
| EP-1351565-A1 | CHEMICAL INHIBITORS OF MISMATCH REPAIR | Morphotek Inc. (US) | 2003-10-15 | — | — | EP | claimed |
| US-20030143586-A1 | Genetic hypermutability of plants for gene discovery and diagnosis | MORPHOTEK, INC. | 2003-07-31 | — | — | US | claimed |
| US-20030091997-A1 | Chemical inhibitors of mismatch repair | EISAI, INC. | 2003-05-15 | — | — | US | claimed |
| WO-2003031937-A2 | GENETIC HYPERMUTABILITY OF PLANTS FOR GENE DISCOVERY AND DIAGNOSIS | MORPHOTEK, INC. (US) | 2003-04-17 | — | — | WO | claimed |
| US-20030068808-A1 | Methods for generating antibiotic resistant microbes and novel antibiotics | MORPHOTEK, INC. | 2003-04-10 | — | — | US | claimed |
| WO-2003012130-A1 | METHODS FOR GENERATING ANTIBIOTIC RESISTANT MICROBES AND NOVEL ANTIBIOTICS | MORPHOTEK INC. (US) | 2003-02-13 | — | — | WO | claimed |
| WO-2002054856-A1 | CHEMICAL INHIBITORS OF MISMATCH REPAIR | MORPHOTEK INC. (US) | 2002-07-18 | — | — | WO | claimed |
| EP-4091578-B1 | METHOD FOR PRODUCING PLATE DENTURE | TOKUYAMA DENTAL CORP (JP) | 2024-10-09 | — | — | EP | disclosed |
| US-11857385-B2 | Method of producing plate denture, curable composition for stereolithography, and plate denture production kit | TOKUYAMA DENTAL CORPORATION (JP) | 2024-01-02 | — | — | US | disclosed |
| US-20230137898-A1 | METHOD OF PRODUCING PLATE DENTURE, CURABLE COMPOSITION FOR STEREOLITHOGRAPHY, AND PLATE DENTURE PRODUCTION KIT | TOKUYAMA DENTAL CORPORATION (JP) | 2023-05-04 | — | — | US | disclosed |
| WO-2002054856-A1 | CHEMICAL INHIBITORS OF MISMATCH REPAIR | MORPHOTEK INC. (US) | 2002-07-18 | — | — | WO | disclosed |
| US-20020055064-A1 | Anti-reflective coating composition, multilayer photoresist material using the same, and method for forming pattern | TOKYO OHKA KOGYO CO., LTD. (JP) | 2002-05-09 | — | — | US | disclosed |
| US-20010044080-A1 | Method for forming a finely patterned photoresist layer | TOKYO OHKA KOGYO CO., LTD. (JP) | 2001-11-22 | — | — | US | disclosed |
| US-20010036998-A1 | Anti-reflective coating-forming composition | TOKYO OHKA KOGYO CO., LTD. (JP) | 2001-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030091997-A1 | Chemical inhibitors of mismatch repair | MSH2, MSH6, PMS2 | ALDH1A1 347/4885CYP1A2 2746/4885HSD17B10 2040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.