Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399561 | 0.85 | IDO1 (0.55) | SIGMAR1IDO1CTSKNAMPTNPC1 | |
| SCHEMBL572740 | 0.82 | IDO1 (0.60) | SIGMAR1IDO1CTSKNAMPTNPC1 | |
| SCHEMBL13192909 | 0.82 | NPSR1 (0.55) | SIGMAR1IDO1CTSKNAMPTCA1 | |
| SCHEMBL4898925 | 0.82 | NPSR1 (0.55) | SIGMAR1IDO1CTSKNAMPTCA1 | |
| SCHEMBL8573380 | 0.81 | SIGMAR1 (0.54) | SIGMAR1IDO1CTSKNAMPTNPC1 | |
| SCHEMBL2345111 | 0.81 | CTSK (0.44) | SIGMAR1IDO1CTSKCTSSSYK | |
| SCHEMBL7141839 | 0.81 | CA12 (0.50) | SIGMAR1CTSKNPC1RAB9AMAPT | |
| SCHEMBL4707263 | 0.79 | SYK (0.52) | SIGMAR1IDO1CTSKCTSSCA1 | |
| SCHEMBL13613756 | 0.78 | HTT (0.48) | IDO1CTSKMAPTCTSSSYK | |
| SCHEMBL25048413 | 0.77 | CA1 (0.60) | SIGMAR1IDO1CTSKNAMPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110040087-A1 | PEPTIDE TURN MIMETICS | MIMETICA PTY LTD. (AU) | 2011-02-17 | — | — | US | disclosed |
| US-20090275727-A1 | Peptide turn mimetics | MIMETICA PTY LIMITED (AU) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275727-A1 | Peptide turn mimetics | IAPP, GLP1R, VIP | SIGMAR1 4359/4885IDO1 2466/4885CTSK 1231/4885 |
| US-20110040087-A1 | PEPTIDE TURN MIMETICS | VIP, IAPP, SCTR | SIGMAR1 1460/4885IDO1 2875/4885CTSK 1905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.