SCHEMBL12880693

SCHEMBL12880693

CN1C=C/C(=C\C=C\c2ccc(O)c(C(=O)O)c2)c2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.49
HNF4A P41235 1/20 0.49
PTPN2 P17706 1/20 0.46
PTPN6 P29350 1/20 0.46
PTGS2 P35354 1/20 0.42
PIM1 P11309 1/20 0.40
LCK P06239 1/20 0.40
APP P05067 5/20 0.39
ACMSD Q8TDX5 1/20 0.38
MCL1 Q07820 1/20 0.38
MAOB P27338 4/20 0.37
DHODH Q02127 1/20 0.37
MAOA P21397 1/20 0.37
SLC7A11 Q9UPY5 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12866258 0.86 XDH (0.43) LCKAPPMCL1
SCHEMBL12866229 0.81 XDH (0.43) PTGS2APPMCL1MAOBMAOA
SCHEMBL12976267 0.77 MAPT (0.32) APPMCL1MAOBMAOA
SCHEMBL10625415 0.68 MAPT (0.46) APPMCL1
SCHEMBL10625407 0.68 MAPT (0.46) APPMCL1
SCHEMBL7825843 0.68 CA2 (0.39) MCL1
SCHEMBL21385358 0.68 PTPN1 (1.00) PTPN1HNF4APTPN2PTPN6PTGS2
SCHEMBL673426 0.68 PTPN1 (1.00) PTPN1HNF4APTPN2PTPN6PTGS2
SCHEMBL30075246 0.68 PTPN1 (1.00) PTPN1HNF4APTPN2PTPN6PTGS2
SCHEMBL12881135 0.67 PTPN1 (0.43) PTPN1HNF4APTPN2PTPN6PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2262050-B1 Photoelectric conversion element sensitized with methine dyes NIPPON KAYAKU KK (JP) 2013-09-04 EP disclosed
US-8338700-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-12-25 US disclosed
US-8338701-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-12-25 US disclosed
US-20110030801-A1 Dye-Sensitized Photoelectric Conversion Device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-02-10 US disclosed
US-20110031446-A1 Dye-Sensitized Photoelectric Conversion Device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-02-10 US disclosed
US-7851701-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2010-12-14 US disclosed
US-7851701-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2010-12-14 US disclosed