Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7830522 | 0.78 | CTDSP1 (0.39) | CA2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL7830519 | 0.78 | CTDSP1 (0.39) | CA2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL7826328 | 0.72 | MAPT (0.46) | CA2CA1KMT2AMEN1MAPT | |
| SCHEMBL10625407 | 0.69 | MAPT (0.46) | KMT2AMEN1MAPTPOLBKDM4E | |
| SCHEMBL10625415 | 0.69 | MAPT (0.46) | KMT2AMEN1MAPTPOLBKDM4E | |
| SCHEMBL13669200 | 0.69 | PRMT1 (0.42) | KMT2AMEN1MAPTPOLBKDM4E | |
| SCHEMBL5512417 | 0.66 | MEN1 (0.35) | KMT2AMEN1MAPTPOLBKDM4E | |
| SCHEMBL10455465 | 0.65 | CA2 (0.65) | CA2CA1KMT2AMEN1MAPT | |
| SCHEMBL10455464 | 0.65 | CA2 (0.65) | CA2CA1KMT2AMEN1MAPT | |
| SCHEMBL12866258 | 0.64 | XDH (0.43) | KMT2AMEN1MAPTPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |