Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 7/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 7/20 | 0.42 |
| ▸ | PDE5A | O76074 | 4/20 | 0.42 |
| ▸ | PDE4A | P27815 | 4/20 | 0.42 |
| ▸ | PDE1A | P54750 | 4/20 | 0.42 |
| ▸ | PDE1B | Q01064 | 4/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.42 |
| ▸ | PDE1C | Q14123 | 4/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 6/20 | 0.41 |
| ▸ | TUBB | P07437 | 6/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL192576 | 0.88 | TUBB4A (0.46) | PDE3BPDE3APDE5APDE4APDE1A | |
| SCHEMBL128801 | 0.84 | PDE10A (0.37) | PDE3BPDE3APDE5APDE4APDE1A | |
| SCHEMBL151891 | 0.82 | PDE10A (0.55) | PDE3BPDE3APDE5APDE4APDE1A | |
| SCHEMBL127901 | 0.75 | PDE10A (0.39) | PDE3BPDE3APDE5APDE4APDE1A | |
| SCHEMBL129991 | 0.74 | RAD52 (0.40) | PDE3BPDE3APDE5APDE4APDE1A | |
| SCHEMBL149392 | 0.73 | PDE10A (0.55) | PDE3BPDE3APDE5APDE4APDE1A | |
| SCHEMBL8555054 | 0.70 | PDE10A (0.56) | PDE3BPDE3APDE5APDE4APDE1A | |
| SCHEMBL147885 | 0.68 | PDE10A (0.75) | PDE3BPDE3APDE5APDE4APDE1A | |
| SCHEMBL11722846 | 0.68 | TUBB4A (0.49) | PDE3BPDE3APDE5APDE4APDE1A | |
| Hydrochloric Acid SCHEMBL11722812 | 0.67 | PDE10A (0.48) | PDE3BPDE3APDE5APDE4APDE1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9227966-B2 | Antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-01-05 | — | — | US | disclosed |
| US-8933096-B2 | Antimicrobial agents | Rugers, The State University of New Jersey (US) | 2015-01-13 | — | — | US | disclosed |
| US-20140315939-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-10-23 | — | — | US | disclosed |
| US-20130116278-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2013-05-09 | — | — | US | disclosed |
| US-20120059026-A1 | ANTIMICROBIAL AGENTS | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116278-A1 | ANTIMICROBIAL AGENTS | MRPL21, ARG1, RPP30 | PDE3B 1851/4885PDE3A 1652/4885PDE5A 2129/4885 |
| US-20120059026-A1 | ANTIMICROBIAL AGENTS | ZYX, Q6ZSR9, ZC3HAV1L | PDE3B 1735/4885PDE3A 1963/4885PDE5A 2509/4885 |
| US-20140315939-A1 | ANTIMICROBIAL AGENTS | ZYX, Q6ZSR9, ZC3HAV1L | PDE3B 2124/4885PDE3A 2410/4885PDE5A 2633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.