Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.71 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.40 |
| ▸ | TTK | P33981 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | LSS | P48449 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5915632 | 0.84 | TAAR1 (1.00) | TAAR1HRH3ALDH1A1TSHRPYCR1 | |
| SCHEMBL12679031 | 0.79 | HRH3 (1.00) | TAAR1HRH3ALDH1A1TSHRPYCR1 | |
| SCHEMBL11057086 | 0.75 | ALDH1A1 (0.53) | TAAR1ALDH1A1TSHR | |
| SCHEMBL15889318 | 0.75 | ALDH1A1 (0.53) | TAAR1ALDH1A1TSHR | |
| SCHEMBL15889317 | 0.75 | ALDH1A1 (0.53) | TAAR1ALDH1A1TSHR | |
| SCHEMBL24735547 | 0.75 | TSHR (1.00) | TAAR1HRH3ALDH1A1TSHRPYCR1 | |
| SCHEMBL5014268 | 0.75 | TSHR (1.00) | TAAR1HRH3ALDH1A1TSHRPYCR1 | |
| SCHEMBL27766437 | 0.75 | TSHR (1.00) | TAAR1HRH3ALDH1A1TSHRPYCR1 | |
| SCHEMBL15900 | 0.75 | TSHR (1.00) | TAAR1HRH3ALDH1A1TSHRPYCR1 | |
| SCHEMBL12885310 | 0.75 | TSHR (0.52) | TAAR1TSHRHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7880037-B2 | Phosphonium supported triphenylphosphine; for controlling solubility of a molecule; oxidation of Cinnamyl Alcohol using above catalyst system | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2011-02-01 | — | — | US | disclosed |
| US-20070197477-A1 | PHOSPHONIUM SALTS DERIVATIVES | VALORISATION-RECHERECHE (CA) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197477-A1 | PHOSPHONIUM SALTS DERIVATIVES | PI4K2A, PIP4K2A, PI4K2B | TAAR1 2882/4885HRH3 4195/4885ALDH1A1 3806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.