Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 1/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | PGR | P06401 | 1/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | DRD1 | P21728 | 1/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | HRH2 | P25021 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.57 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19787795 | 0.93 | BLM (0.59) | MLNRNR1I2PGRADRB1ADORA3 | |
| SCHEMBL30735656 | 0.93 | BLM (0.59) | MLNRNR1I2PGRADRB1ADORA3 | |
| SCHEMBL12889983 | 0.86 | PRMT1 (0.53) | MLNRNR1I2PGRADRB1ADORA3 | |
| SCHEMBL14883332 | 0.85 | PRMT1 (0.52) | MLNRNR1I2PGRADRB1ADORA3 | |
| SCHEMBL10111609 | 0.85 | MLNR (0.40) | MLNRNR1I2PGRADRB1ADORA3 | |
| SCHEMBL17992180 | 0.84 | MLNR (0.65) | MLNRNR1I2PGRADRB1ADORA3 | |
| Water SCHEMBL8441170 | 0.83 | MLNR (0.64) | MLNRNR1I2PGRADRB1ADORA3 | |
| SCHEMBL16558872 | 0.83 | BLM (0.41) | MLNRNR1I2PGRADRB1ADORA3 | |
| SCHEMBL10111579 | 0.83 | MAPT (0.41) | MLNRNR1I2PGRADRB1ADORA3 | |
| SCHEMBL13172794 | 0.83 | MAPT (0.41) | MLNRNR1I2PGRADRB1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078464-A1 | EPSILON-POLY-L-LYSINE-BASED DRUG CONJUGATE, INTERMEDIATE THEREOF, AND APPLICATION THEREOF | 上海弼领生物技术有限公司 | 2023-05-11 | — | — | WO | disclosed |
| US-20160222212-A1 | Asulfonate Discrete PEG Based Dyes | EQUIP, LLC (US) | 2016-08-04 | — | — | US | disclosed |
| US-9302018-B2 | Fluorescent probe for imaging lymph nodes | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2016-04-05 | — | — | US | disclosed |
| US-20150073154-A1 | Discrete PEG Based Dyes | EQUIP, LLC (US) | 2015-03-12 | — | — | US | disclosed |
| US-20140369935-A1 | LIPOSOME COMPOSITE BODY | NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) | 2014-12-18 | — | — | US | disclosed |
| US-20130129631-A1 | Fluorescent Probe for Imaging Lymph Nodes | NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) | 2013-05-23 | — | — | US | disclosed |
| US-8343463-B2 | Optical imaging agent | NUMIRA BIOSCIENCES INC. (US) | 2013-01-01 | — | — | US | disclosed |
| US-20110027191-A1 | OPTICAL IMAGING AGENT | NUMIRA BIOSCIENCES, INC. (US) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130129631-A1 | Fluorescent Probe for Imaging Lymph Nodes | PLIN5, LIPA, LY6K | MLNR 52/4885NR1I2 2617/4885PGR 3184/4885 |
| US-20110027191-A1 | OPTICAL IMAGING AGENT | TNNC1, TNNI3, MB | MLNR 1187/4885NR1I2 2024/4885PGR 4045/4885 |
| US-20150073154-A1 | Discrete PEG Based Dyes | MKI67, MUC1, TP53 | MLNR 1900/4885NR1I2 1378/4885PGR 974/4885 |
| US-20140369935-A1 | LIPOSOME COMPOSITE BODY | PLIN5, LIPA, NPC1L1 | MLNR 966/4885NR1I2 2121/4885PGR 3458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.