Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.72 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.72 |
| ▸ | METAP1 | P53582 | 3/20 | 0.62 |
| ▸ | CRHBP | P24387 | 1/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | APP | P05067 | 5/20 | 0.54 |
| ▸ | SNCA | P37840 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1249305 | 1.00 | PIM1 (0.72) | PIM1PIM2METAP1CRHBPCRHR2 | |
| SCHEMBL15347679 | 0.87 | CRHBP (0.72) | PIM1PIM2METAP1CRHBPCRHR2 | |
| SCHEMBL15347480 | 0.87 | CRHBP (0.72) | PIM1PIM2METAP1CRHBPCRHR2 | |
| SCHEMBL12892048 | 0.87 | CRHBP (0.72) | PIM1PIM2METAP1CRHBPCRHR2 | |
| SCHEMBL2544392 | 0.84 | PIM1 (1.00) | PIM1PIM2METAP1CRHBPCRHR2 | |
| SCHEMBL1248777 | 0.84 | PIM1 (1.00) | PIM1PIM2METAP1CRHBPCRHR2 | |
| SCHEMBL1248775 | 0.84 | PIM1 (1.00) | PIM1PIM2METAP1CRHBPCRHR2 | |
| SCHEMBL22409611 | 0.83 | PIM1 (0.67) | PIM1PIM2METAP1GSK3BMAPT | |
| SCHEMBL22423780 | 0.83 | PIM1 (0.67) | PIM1PIM2METAP1GSK3BMAPT | |
| SCHEMBL13846678 | 0.83 | PIM1 (0.67) | PIM1PIM2METAP1GSK3BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7879893-B2 | Zinc binding ligand; sustained release of insulin | NOVO NORDISK A/S (DK) | 2011-02-01 | — | — | US | disclosed |
| US-7879893-B2 | Zinc binding ligand; sustained release of insulin | NOVO NORDISK A/S (DK) | 2011-02-01 | — | — | US | disclosed |
| US-20090123563-A1 | Pharmaceutical Preparations Comprising Insulin, Zinc Ions and Zinc-Binding Ligand | NOVO NORDISK A/S (DK) | 2009-05-14 | — | — | US | disclosed |
| US-20090123563-A1 | Pharmaceutical Preparations Comprising Insulin, Zinc Ions and Zinc-Binding Ligand | NOVO NORDISK A/S (DK) | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090123563-A1 | Pharmaceutical Preparations Comprising Insulin, Zinc Ions and Zinc-Binding Ligand | IAPP, IRS1, HBB | PIM1 3773/4885PIM2 4301/4885METAP1 1520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.