SCHEMBL1289304

SCHEMBL1289304

CO[Si](C)(OC)OC(C)=O

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3917985 0.97 ALDH1A1 (0.40) ALDH1A1MGAMGAASIMGAM2
SCHEMBL3912225 0.97 ALDH1A1 (0.40) ALDH1A1MGAMGAASIMGAM2
SCHEMBL838347 0.94 ALDH1A1 (0.42) ALDH1A1MGAMGAASIMGAM2
SCHEMBL63651 0.84 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL23781789 0.81 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL28037449 0.81 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL16616580 0.81 ALDH1A1 (0.37) ALDH1A1MGAMGAASIMGAM2
SCHEMBL28880797 0.81 TSHR (0.37) ALDH1A1TSHR
SCHEMBL4582447 0.81
SCHEMBL10794628 0.79 ALDH1A1 (0.37) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 529 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12378362-B2 Polydiorganosiloxane preparation DOW SILICONES CORPORATION (US) 2025-08-05 US claimed
CN-114901725-B Polydiorganosiloxane preparation 美国陶氏有机硅公司 2023-09-08 CN claimed
US-20230013216-A1 POLYDIORGANOSILOXANE PREPARATION DOW SILICONES CORPORATION 2023-01-19 US claimed
EP-4077482-A1 POLYDIORGANOSILOXANE PREPARATION Dow Silicones Corporation (US) 2022-10-26 EP claimed
CN-114901725-A Preparation of polydiorganosiloxane 美国陶氏有机硅公司 2022-08-12 CN claimed
WO-2021119972-A1 POLYDIORGANOSILOXANE PREPARATION DOW SILICONES CORPORATION (US) 2021-06-24 WO claimed
CN-122095029-A Molded article and curable composition 2026-05-26 CN disclosed
US-12624168-B2 Methods for making polyfunctional organosiloxanes and compositions containing same DOW SILICONES CORPORATION (US) 2026-05-12 US disclosed
EP-4086705-B1 TONER CANON KK (JP) 2026-03-25 EP disclosed
EP-4012501-B1 EXTERNAL ADDITIVE FOR TONER, TONER AND IMAGE FORMING APPARATUS CANON KK (JP) 2026-02-11 EP disclosed
EP-3654105-B1 PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS CANON KK (JP) 2026-01-28 EP disclosed
EP-4519346-B1 SILICONE-POLYETHER COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS DOW SILICONES CORP (US) 2026-01-14 EP disclosed
US-12497509-B2 Method for manufacturing a silicone elastomer article using a 3D printer ELKEM SILICONES FRANCE SAS (FR) 2025-12-16 US disclosed
WO-2012134784-A1 COMPOSITIONS CONTAINING PHOSPHONATE CATALYSTS AND METHODS FOR THE PREPARATION AND USE OF THE COMPOSITIONS DOW CORNING CORPORATION (US) 2012-10-04 WO disclosed
WO-2012134786-A1 COMPOSITIONS CONTINING SULFONIC ACID CATALYSTS AND METHODS FOR THE PREPARATION AND USE OF THE COMPOSITIONS DOW CORNING CORPORATION (US) 2012-10-04 WO disclosed
WO-2012134788-A1 COMPOSITIONS CONTAINING PHOSPHATE CATALYSTS AND METHODS FOR THE PREPARATION AND USE OF THE COMPOSITIONS DOW CORNING CORPORATION (US) 2012-10-04 WO disclosed
WO-2012047312-A1 BIODEGRADABLE HYDROPHOBIC CELLULOSIC SUBSTRATES AND METHODS FOR THEIR PRODUCTION USING REACTIVE SILANES DOW CORNING CORPORATION (US) 2012-04-12 WO disclosed
US-20090277559-A1 METHOD FOR VULCANIZATION-ADHERING RUBBER COMPOSITION TO ADHERENT OF BRASS OR PLATED WITH BRASS, REINFORCING MEMBER FOR RUBBER ARTICLE, RUBBER-REINFORCING MEMBER COMPOSITE AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2009-11-12 US disclosed
EP-1840158-B1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2009-02-18 EP disclosed
EP-1840158-A1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE Bridgestone Corporation (JP) 2007-10-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624168-B2 Methods for making polyfunctional organosiloxanes and compositions containing same HAO2, H1-2, HRH2 ALDH1A1 596/4885MGAM 4562/4885GAA 2348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.