SCHEMBL838347

SCHEMBL838347

CO[Si](C)(OC(C)=O)OC(C)=O

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
TSHR P16473 1/20 0.35
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1289304 0.94 ALDH1A1 (0.42) ALDH1A1TSHRMGAMGAASI
SCHEMBL3917985 0.92 ALDH1A1 (0.40) ALDH1A1TSHRMGAMGAASI
SCHEMBL3912225 0.92 ALDH1A1 (0.40) ALDH1A1TSHRMGAMGAASI
SCHEMBL63651 0.84 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL23781789 0.81 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL28037449 0.81 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL16616580 0.81 ALDH1A1 (0.37) ALDH1A1TSHRMGAMGAASI
SCHEMBL28880797 0.81 TSHR (0.37) ALDH1A1TSHR
SCHEMBL10794628 0.79 ALDH1A1 (0.37) ALDH1A1TSHR
SCHEMBL28880785 0.78 ALDH1A1 (0.34) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 476 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12378362-B2 Polydiorganosiloxane preparation DOW SILICONES CORPORATION (US) 2025-08-05 US claimed
US-20230013216-A1 POLYDIORGANOSILOXANE PREPARATION DOW SILICONES CORPORATION 2023-01-19 US claimed
EP-4077482-A1 POLYDIORGANOSILOXANE PREPARATION Dow Silicones Corporation (US) 2022-10-26 EP claimed
WO-2021119972-A1 POLYDIORGANOSILOXANE PREPARATION DOW SILICONES CORPORATION (US) 2021-06-24 WO claimed
CN-122095029-A Molded article and curable composition 2026-05-26 CN disclosed
US-12624168-B2 Methods for making polyfunctional organosiloxanes and compositions containing same DOW SILICONES CORPORATION (US) 2026-05-12 US disclosed
US-20260118791-A1 TONER CANON KK (JP) 2026-04-30 US disclosed
EP-4086705-B1 TONER CANON KK (JP) 2026-03-25 EP disclosed
EP-4012501-B1 EXTERNAL ADDITIVE FOR TONER, TONER AND IMAGE FORMING APPARATUS CANON KK (JP) 2026-02-11 EP disclosed
EP-3654105-B1 PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS CANON KK (JP) 2026-01-28 EP disclosed
EP-4519346-B1 SILICONE-POLYETHER COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS DOW SILICONES CORP (US) 2026-01-14 EP disclosed
US-12497509-B2 Method for manufacturing a silicone elastomer article using a 3D printer ELKEM SILICONES FRANCE SAS (FR) 2025-12-16 US disclosed
WO-2012047312-A1 BIODEGRADABLE HYDROPHOBIC CELLULOSIC SUBSTRATES AND METHODS FOR THEIR PRODUCTION USING REACTIVE SILANES DOW CORNING CORPORATION (US) 2012-04-12 WO disclosed
US-8142856-B2 Preparing hydrolyzate containing polysiloxanes by hydrolyzing hydrolysable silane or hydrolysable silane mixture in presence of acid hydrolysis catalyst andcombining polysiloxane hydrolyzate with mineral and/or filler and optionally with water and/or a catalyst for condensation of the hydrolyzate DOW CORNING CORPORATION (US) 2012-03-27 US disclosed
EP-1448714-B1 SYNTHESIS AND USE ALKYLALKOXYACYLOXYSILANES AND BLENDS THEREOF FOR USE AS A CROSSLINKING AGENT IN MOISTURE CURING RTV'S MOMENTIVE PERFORMANCE MAT INC (US) 2011-08-24 EP disclosed
US-20080286474-A1 Hydrophobing Minerals and Filler Materials DOW SILICONES CORPORATION 2008-11-20 US disclosed
CN-101223117-A Hydrophobing minerals and filler materials DOW CORNING (US) 2008-07-16 CN disclosed
EP-1904415-A2 HYDROPHOBING MINERALS AND FILLER MATERIALS Dow Corning Corporation (US) 2008-04-02 EP disclosed
WO-2007009935-A2 HYDROPHOBING MINERALS AND FILLER MATERIALS DOW CORNING CORPORATION (US) 2007-01-25 WO disclosed
US-4220748-A CONTAINING AN ACETOXY GROUP-CONTAINING SILANE COMPOUND TOSHIBA SILICONE CO., LTD. (JP) 1980-09-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260118791-A1 TONER MSR1, H1-2, TAAR1 ALDH1A1 2569/4885TSHR 165/4885MGAM 3616/4885
US-12624168-B2 Methods for making polyfunctional organosiloxanes and compositions containing same HAO2, H1-2, HRH2 ALDH1A1 596/4885TSHR 549/4885MGAM 4562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.