SCHEMBL1289345

SCHEMBL1289345

CC(C)[CH]Cc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.52
TAAR1 Q96RJ0 5/20 0.44
SIGMAR1 Q99720 4/20 0.44
SLC6A2 P23975 3/20 0.44
SLC6A4 P31645 2/20 0.44
SLC6A3 Q01959 2/20 0.44
MAOA P21397 1/20 0.44
CYP2A6 P11509 1/20 0.44
ADORA2A P29274 1/20 0.44
ADORA1 P30542 1/20 0.44
TP53 P04637 1/20 0.42
SLC18A2 Q05940 1/20 0.41
CYP2D6 P10635 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
TRPA1 O75762 2/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
ARG2 P78540 1/20 0.40
CALM1 P0DP23 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4155331 0.81 MAOB (0.48) MAOBTAAR1SIGMAR1SLC6A2SLC6A4
SCHEMBL3295095 0.81 MAOB (0.48) MAOBTAAR1SIGMAR1SLC6A2SLC6A4
SCHEMBL8174260 0.81 MAOB (0.48) MAOBTAAR1SIGMAR1SLC6A2SLC6A4
SCHEMBL5680524 0.79 MAOB (0.46) MAOBTAAR1SIGMAR1SLC6A2SLC6A4
SCHEMBL15365066 0.79 MAOB (0.46) MAOBTAAR1SIGMAR1SLC6A2SLC6A4
SCHEMBL11098509 0.79 SIGMAR1 (0.50) MAOBTAAR1SIGMAR1SLC6A2SLC6A4
SCHEMBL794180 0.79 MAOB (0.46) MAOBTAAR1SIGMAR1SLC6A2SLC6A4
SCHEMBL10902102 0.78 IDO1 (0.42) MAOBTAAR1MAOACYP2A6TP53
SCHEMBL11658046 0.78 CYP1A2 (0.45) SIGMAR1CYP2D6
SCHEMBL11547165 0.78 PTGES (0.48) MAOBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106608939-B The preparation method of catalytic component for olefinic polymerization 中国石油化工股份有限公司 2019-08-20 CN claimed
CN-110099930-A modified conjugated diene polymer and preparation method thereof 株式会社LG化学 2019-08-06 CN claimed
CN-106608940-B The preparation method of catalytic component for olefinic polymerization 中国石油化工股份有限公司 2019-06-28 CN claimed
CN-104558290-B One kind being used for catalyst component for olefin polymerization and catalyst 中国石油化工股份有限公司 2018-11-02 CN claimed
CN-104558291-B One kind is used for olefin polymerization catalysis preparation method 中国石油化工股份有限公司 2017-05-31 CN claimed
CN-104558292-B One kind is used for olefin polymerization catalysis preparation method 中国石油化工股份有限公司 2017-05-31 CN claimed
CN-106608939-A Preparation method of catalyst component for olefin polymerization 中国石油化工股份有限公司 2017-05-03 CN claimed
CN-106608940-A Preparation method for catalyst components used for olefin polymerization 中国石油化工股份有限公司 2017-05-03 CN claimed
CN-104558293-B Catalyst component for olefin polymerization and catalyst 中国石油化工股份有限公司 2017-02-15 CN claimed
US-20130040917-A1 Phenazopyridine Compounds PINNACLE PHARMACEUTICALS, INC. (US) 2013-02-14 US claimed
EP-0812839-A1 Irreversible HIV protease inhibitors, compositions containing same and process for the preparation thereof LG Chemical Limited (KR) 1997-12-17 EP claimed
US-5670517-A MULTISTAGE SYNTHESIS WITH EPOXIDATION, DECARBONYLATION, COUPLING BY AMIDATION THEN DECARBONYLATION LG CHEMICAL LIMITED (KR) 1997-09-23 US claimed
WO-2024129756-A1 SITE-SPECIFIC ENGINEERED CYSTEINE ANTIBODY DRUG CONJUGATES SEAGEN INC. (US) 2024-06-20 WO disclosed
CN-110968218-B Touch display panel and preparation method thereof 合肥维信诺科技有限公司 2024-03-01 CN disclosed
WO-2024036329-A2 CYTOTOXIC COMPOUNDS AND CONJUGATES THEREOF SEAGEN INC. (US) 2024-02-15 WO disclosed
WO-2023178289-A2 CAMPTOTHECIN CONJUGATES SEAGEN INC. (US) 2023-09-21 WO disclosed
US-4343732-A HEAT AND WEATHER RESISTANCE, BISPHENOL PHOSPHATE STABILIZER AJINOMOTO COMPANY INCORPORATED (JP) 1982-08-10 US disclosed
EP-0049120-A1 Phenethylether derivatives, process for preparing same and uses thereof in combatting tobacco beetles and in augmenting or enhancing the aroma of perfumes, colognes and perfumed articles INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1982-04-07 EP disclosed
EP-0024897-A2 Chromogen solutions and pressure-sensitive mark-recording systems MONSANTO EUROPE S.A./N.V. (BE) 1981-03-11 EP disclosed
US-4136100-A BLUE-VIOLET TO GREEN-BLUE DYEINGS ON CELLULOSE TEXTILES BASF AKTIENGESELLSCHAFT (DE) 1979-01-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130040917-A1 Phenazopyridine Compounds CYP3A5, CYP3A4, CYP2D6 MAOB 264/4885TAAR1 851/4885SIGMAR1 118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.