SCHEMBL1289403

SCHEMBL1289403

O=C(O)c1ccc(-c2ccc(C(=O)O)cc2)cc1.O=C(O)c1ccc(Cc2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.70
CA1 P00915 1/20 0.70
CA2 P00918 1/20 0.70
CA9 Q16790 1/20 0.70
CA14 Q9ULX7 1/20 0.70
SRD5A2 P31213 4/20 0.62
RARB P10826 6/20 0.60
ALDH1A1 P00352 2/20 0.58
BCL2L1 Q07817 1/20 0.58
BAD Q92934 1/20 0.58
TSHR P16473 2/20 0.57
TP53 P04637 1/20 0.57
RXRA P19793 1/20 0.57
RXRB P28702 1/20 0.57
KMT2A Q03164 2/20 0.56
MEN1 O00255 1/20 0.56
RARA P10276 1/20 0.56
MAPT P10636 1/20 0.56
MTOR P42345 1/20 0.56
EPHX2 P34913 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL68390 0.93 SRD5A2 (0.69) CA12CA1CA2CA9CA14
Hydrochloric Acid SCHEMBL7133360 0.90 SRD5A2 (0.67) CA12CA1CA2CA9CA14
Hydrochloric Acid SCHEMBL25188150 0.90 SRD5A2 (0.67) CA12CA1CA2CA9CA14
SCHEMBL5482345 0.86 SRD5A2 (0.71) CA12CA1CA2CA9CA14
Benzoic Acid SCHEMBL7064148 0.86 SRD5A2 (0.71) CA12CA1CA2CA9CA14
SCHEMBL502598 0.86 SRD5A2 (0.71) CA12CA1CA2CA9CA14
SCHEMBL11673315 0.86 SRD5A2 (0.62) CA12CA1CA2CA9CA14
Terephthalic Acid SCHEMBL9577834 0.84 TSHR (0.80) CA12CA1CA2CA9CA14
SCHEMBL69873 0.84 TSHR (0.80) CA12CA1CA2CA9CA14
SCHEMBL2637326 0.84 TSHR (0.80) CA12CA1CA2CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012047360-A1 FUNCTIONALIZED POLYETHYLENE TEREPHTHALATE POLYMERS, FUNCTIONALIZED DERIVATIVE POLYMERS OF POLYETHYLENE TEREPHTHALATE, METHODS OF MAKING AND USING SAME FELICE KRISTOPHER M (US) 2012-04-12 WO claimed