Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HNF4A | P41235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12894184 | 0.88 | MEN1 (0.43) | ALDH1A1KMT2ALMNAMEN1HPRT1 | |
| SCHEMBL15049917 | 0.80 | ALDH1A1 (0.45) | ALDH1A1KMT2ALMNAMEN1HPRT1 | |
| SCHEMBL18622105 | 0.79 | ALDH1A1 (0.55) | ALDH1A1KMT2ALMNAMEN1HPRT1 | |
| SCHEMBL12894172 | 0.78 | TSHR (0.50) | ALDH1A1KMT2ALMNAMEN1HPRT1 | |
| SCHEMBL7056500 | 0.78 | MEN1 (0.39) | ALDH1A1KMT2ALMNAMEN1HPRT1 | |
| SCHEMBL29853852 | 0.76 | ALDH1A1 (0.43) | ALDH1A1KMT2ALMNAMEN1NPSR1 | |
| SCHEMBL4648011 | 0.76 | ALDH1A1 (0.43) | ALDH1A1KMT2ALMNAMEN1NPSR1 | |
| SCHEMBL12894170 | 0.76 | S100A4 (0.46) | ALDH1A1KMT2ALMNAMEN1NPSR1 | |
| SCHEMBL12894174 | 0.76 | ALDH1A1 (0.43) | ALDH1A1KMT2ALMNAMEN1CASP6 | |
| SCHEMBL7058541 | 0.76 | ALDH1A1 (0.44) | ALDH1A1KMT2ALMNAMEN1HPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028350-A1 | PHOTOCLEAVABLE PROTECTING GROUPS | AFFYMETRIX, INC. (US) | 2011-02-03 | — | — | US | disclosed |
| US-20090076295-A1 | PHOTOCLEAVABLE PROTECTING GROUPS | AFFYMETRIX, INC. (US) | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076295-A1 | PHOTOCLEAVABLE PROTECTING GROUPS | POLL, PCNA, ERCC4 | ALDH1A1 1340/4885KMT2A 3720/4885LMNA 467/4885 |
| US-20110028350-A1 | PHOTOCLEAVABLE PROTECTING GROUPS | POLL, ERCC5, FBL | ALDH1A1 2363/4885KMT2A 3611/4885LMNA 520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.