SCHEMBL4648011

SCHEMBL4648011

CC(=O)OC(C)c1c2ccccc2cc2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.43
HPGD P15428 6/20 0.43
KDM4E B2RXH2 6/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
GLA P06280 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C19 P33261 1/20 0.43
HSD17B10 Q99714 1/20 0.43
MAPT P10636 3/20 0.41
NCEH1 Q6PIU2 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
AKR1B1 P15121 1/20 0.38
CYP3A4 P08684 1/20 0.37
LMNA P02545 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
TP53 P04637 1/20 0.36
MMP12 P39900 1/20 0.36
MAPK1 P28482 1/20 0.35
ATM Q13315 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29853852 1.00 ALDH1A1 (0.43) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL12383183 0.87 ALDH1A1 (0.41) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL9404141 0.85 ALDH1A1 (0.42) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL4647200 0.84 ALDH1A1 (0.44) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL5594212 0.84 ALDH1A1 (0.39) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL11636414 0.81 HCAR2 (0.39) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL2740643 0.80 KMT2A (0.40) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL8372932 0.79 ALDH1A1 (0.40) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL2740653 0.77 RIPK1 (0.39) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL12894166 0.76 ALDH1A1 (0.44) ALDH1A1HPGDMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4091578-B1 METHOD FOR PRODUCING PLATE DENTURE TOKUYAMA DENTAL CORP (JP) 2024-10-09 EP disclosed
US-11857385-B2 Method of producing plate denture, curable composition for stereolithography, and plate denture production kit TOKUYAMA DENTAL CORPORATION (JP) 2024-01-02 US disclosed
US-20230137898-A1 METHOD OF PRODUCING PLATE DENTURE, CURABLE COMPOSITION FOR STEREOLITHOGRAPHY, AND PLATE DENTURE PRODUCTION KIT TOKUYAMA DENTAL CORPORATION (JP) 2023-05-04 US disclosed
EP-4091578-A1 METHOD FOR PRODUCING PLATE DENTURE, CURABLE STEREOLITHOGRAPHIC COMPOSITION, AND PLATE DENTURE PRODUCTION KIT Tokuyama Dental Corporation (JP) 2022-11-23 EP disclosed
CN-114929158-A Method for producing a denture, curable composition for photo-molding, and kit for producing a denture 株式会社德山齿科 2022-08-19 CN disclosed
EP-1591098-B1 Cationically curable composition for dental use TOKUYAMA CORP (JP) 2008-08-13 EP disclosed
US-7365106-B2 Cationically curable composition for dental use TOKUYAMA CORPORATION (JP) 2008-04-29 US disclosed
EP-1431315-B1 Photopolymerization initiator and photopolymerizable composition TOKUYAMA CORP (JP) 2007-10-17 EP disclosed
US-20050250868-A1 Cationically curable composition for dental use TOKUYAMA CORPORATION (JP) 2005-11-10 US disclosed
EP-1591098-A1 Cationically curable composition for dental use TOKUYAMA CORPORATION (JP) 2005-11-02 EP disclosed
US-20040186195-A1 Photopolymerization initiator and photopolymerizable composition TOKUYAMA CORPORATION (JP) 2004-09-23 US disclosed
CN-1513884-A Photopolymerization initiator and composition capable of photopolymerization 株式会社德山 2004-07-21 CN disclosed
EP-1431315-A2 Photopolymerization initiator and photopolymerizable composition Tokuyama Corporation (JP) 2004-06-23 EP disclosed