Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | LPL | P06858 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10330355 | 0.87 | ADRA2A (0.58) | ADRA2AADRA2BADRA2CALDH1A1TSHR | |
| SCHEMBL12680471 | 0.85 | ALDH1A1 (0.61) | ADRA2AADRA2BADRA2CALDH1A1TSHR | |
| SCHEMBL6841550 | 0.85 | ALDH1A1 (0.61) | ADRA2AADRA2BADRA2CALDH1A1TSHR | |
| SCHEMBL14905181 | 0.81 | MAPT (0.42) | ALDH1A1TSHRMAPK1TDP1CYP3A4 | |
| SCHEMBL15014122 | 0.81 | ADRA2A (0.50) | ADRA2AADRA2BADRA2CALDH1A1TSHR | |
| SCHEMBL12679045 | 0.79 | ALDH1A1 (0.74) | ADRA2AADRA2BADRA2CALDH1A1TSHR | |
| SCHEMBL15613386 | 0.79 | HRH3 (0.40) | ALDH1A1TSHRMAPK1TDP1CYP3A4 | |
| SCHEMBL44501 | 0.79 | ALDH1A1 (0.67) | ALDH1A1TSHRMAPK1TDP1CYP3A4 | |
| SCHEMBL17485895 | 0.79 | CHKA (0.47) | ALDH1A1TSHRMAPK1TDP1CYP3A4 | |
| SCHEMBL4400993 | 0.79 | ADRA2A (0.52) | ADRA2AADRA2BADRA2CALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3875281-A1 | LITHOGRAPHIC PRINTING PLATE ORIGINAL PLATE, METHOD FOR PRODUCING LITHOGRAPHIC PRINTING PLATE AND LITHOGRAPHIC PRINTING METHOD | FUJIFILM Corporation (JP) | 2021-09-08 | — | — | EP | disclosed |
| EP-2900234-B1 | CANCER CHEMOTHERAPEUTIC AGENT/FORMULATION, MANUFACTURE AND USE THEREOF | BOSE INST (IN) | 2020-10-28 | — | — | EP | disclosed |
| US-7884108-B2 | tyrosine kinase inhibitors such as N-(3-(6-(4-(1,4-Dimethyl-3-oxopiperazin-2-yl)phenyl amino)-4-methyl-5-oxo-4,5-dihydropyrazin-2-yl)-2-fluorophenyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-2-carboxamide for treating bone disorders, allergic disorders, autoimmune diseases, inflammatory diseases | CGI PHARMACEUTICALS, INC. (US) | 2011-02-08 | — | — | US | disclosed |