Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4400993 | 0.91 | ADRA2A (0.52) | ADRA2AADRA2BADRA2CALDH1A1TSHR | |
| SCHEMBL18323114 | 0.91 | ADRA2A (0.52) | ADRA2AADRA2BADRA2CALDH1A1TSHR | |
| SCHEMBL762882 | 0.91 | ALDH1A1 (0.61) | ADRA2AADRA2BADRA2CALDH1A1TSHR | |
| SCHEMBL8278827 | 0.89 | ALDH1A1 (0.55) | ADRA2AADRA2BADRA2CALDH1A1TSHR | |
| SCHEMBL5741048 | 0.87 | ADRA2A (0.53) | ADRA2AADRA2BADRA2CALDH1A1TSHR | |
| SCHEMBL12680471 | 0.87 | ALDH1A1 (0.61) | ADRA2AADRA2BADRA2CALDH1A1TSHR | |
| SCHEMBL157897 | 0.87 | ADRA2A (0.48) | ADRA2AADRA2BADRA2CALDH1A1HSD17B10 | |
| SCHEMBL128466 | 0.87 | TDP1 (0.62) | ADRA2AADRA2BADRA2CALDH1A1TSHR | |
| SCHEMBL3949344 | 0.87 | ADRA2A (0.48) | ADRA2AADRA2BADRA2CALDH1A1TSHR | |
| SCHEMBL12894331 | 0.87 | ADRA2A (0.48) | ADRA2AADRA2BADRA2CALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9080099-B2 | Fluorine-bridged associations for optoelectronic applications | MERCK PATENT GMBH (DE) | 2015-07-14 | — | — | US | disclosed |
| US-8637853-B2 | Optoelectronic device | MERCK PATENT GMBH (DE) | 2014-01-28 | — | — | US | disclosed |
| US-8445630-B2 | Polymers | BASF SE (DE) | 2013-05-21 | — | — | US | disclosed |
| US-8236968-B2 | 1,4-bis(2-thienylvinyl)benzol derivatives and their use | MERCK PATENT GMBH (DE) | 2012-08-07 | — | — | US | disclosed |
| US-8221906-B2 | Electroluminescent polymers for electronic applications | BASF SE (DE) | 2012-07-17 | — | — | US | disclosed |
| US-20110204351-A1 | NOVEL DIKETOPYRROLOPYRROLE POLYMERS | HEIM INGO | 2011-08-25 | — | — | US | disclosed |
| US-7939818-B2 | Diketopyrrolopyrrole polymers | BASF SE (DE) | 2011-05-10 | — | — | US | disclosed |
| US-20110095283-A1 | FLUORINE-BRIDGED ASSOCIATIONS FOR OPTOELECTRONIC APPLICATIONS | MERCK PATENT GMBH (DE) | 2011-04-28 | — | — | US | disclosed |
| US-20110068329-A1 | OPTOELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2011-03-24 | — | — | US | disclosed |
| US-20110037058-A1 | OPTOELECTRONIC DEVICE | MERCK PATENT GMBH PATENTS & SCIENTIFIC INFORMATION (DE) | 2011-02-17 | — | — | US | disclosed |
| US-20090321686-A1 | 1,4-BIS(2-THIENYLVINYL)BENZOL DERIVATIVES AND THEIR USE | BUESING ARNE | 2009-12-31 | — | — | US | disclosed |
| US-7638594-B2 | Conjugated polymers containing spirobifluorene units and the use thereof | MERCK PATENT GMBH (DE) | 2009-12-29 | — | — | US | disclosed |
| US-20090309068-A1 | NOVEL ELECTROLUMINESCENT POLYMERS FOR ELECTRONIC APPLICATIONS | UDC IRELAND LIMITED (IE) | 2009-12-17 | — | — | US | disclosed |
| US-20090105447-A1 | Novel Polymers | UDC IRELAND LIMITED (IE) | 2009-04-23 | — | — | US | disclosed |
| US-20090005505-A1 | polymeric light emitting diodes; longer operating lifetime; brightness with lower energy; | MERCK PATENT GMBH (DE) | 2009-01-01 | — | — | US | disclosed |
| US-7323533-B2 | Conjugated polymers containing spirobifluorene units and the use thereof | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2008-01-29 | — | — | US | disclosed |
| US-20070265473-A1 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2007-11-15 | — | — | US | disclosed |
| US-7288617-B2 | Conjugated polymers containing spirobifluorene units and fluorene units, and the use thereof | MERCK PATENT GMBH (DE) | 2007-10-30 | — | — | US | disclosed |
| US-20070228359-A1 | Novel Diketopyrrolopyrrole Polymers | CLAP CO., LTD. (KR) | 2007-10-04 | — | — | US | disclosed |
| US-20070060736-A1 | Conjugated polymers containing dihydrophenanthrene units and use thereof | MERCK PATENT GMBH (DE) | 2007-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105447-A1 | Novel Polymers | PLEC, VIM, PUF60 | ADRA2A 4264/4885ADRA2B 4177/4885ADRA2C 4163/4885 |
| US-20090321686-A1 | 1,4-BIS(2-THIENYLVINYL)BENZOL DERIVATIVES AND THEIR USE | TTL, VCL, BRD4 | ADRA2A 1627/4885ADRA2B 775/4885ADRA2C 1663/4885 |
| US-20070265473-A1 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF | ALDH1A2, SELE, PPOX | ADRA2A 2898/4885ADRA2B 2051/4885ADRA2C 2739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.