Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.67 |
| ▸ | FLT3 | P36888 | 4/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | TERT | O14746 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4507613 | 0.99 | RAD52 (0.69) | RAD52POLBRXFP1FLT3MAPK1 | |
| SCHEMBL1289551 | 0.92 | RAD52 (0.56) | RAD52POLBRXFP1FLT3MAPK1 | |
| Hydrochloric Acid SCHEMBL4509102 | 0.91 | RAD52 (0.69) | RAD52POLBRXFP1FLT3MAPK1 | |
| SCHEMBL1289424 | 0.89 | RAD52 (0.59) | RAD52POLBRXFP1FLT3MAPK1 | |
| SCHEMBL1289489 | 0.88 | ALDH1A1 (0.65) | RAD52POLBRXFP1FLT3MAPK1 | |
| Hydrochloric Acid SCHEMBL4502066 | 0.87 | ALDH1A1 (0.67) | RAD52POLBRXFP1FLT3MAPK1 | |
| SCHEMBL10065462 | 0.80 | RAD52 (0.68) | RAD52POLBRXFP1FLT3MAPK1 | |
| SCHEMBL12473416 | 0.78 | KDM4E (0.46) | RAD52POLBRXFP1FLT3MAPK1 | |
| Hydrochloric Acid SCHEMBL4510200 | 0.77 | RAD52 (0.68) | RAD52POLBRXFP1FLT3MAPK1 | |
| SCHEMBL26639491 | 0.76 | ALDH1A1 (0.69) | RAD52POLBRXFP1FLT3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046207-A1 | ANTI-PARASITIC SUBSTITUTED RING FUSED AZINE COMPOUNDS | PARACO TECHNOLOGY LIMITED (NZ) | 2012-04-12 | — | — | WO | disclosed |