Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | FLT3 | P36888 | 7/20 | 0.54 |
| ▸ | TERT | O14746 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | NQO1 | P15559 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1289534 | 0.92 | RAD52 (0.67) | RAD52POLBRXFP1FLT3TERT | |
| SCHEMBL1289424 | 0.92 | RAD52 (0.59) | RAD52POLBRXFP1FLT3TERT | |
| Hydrochloric Acid SCHEMBL4507613 | 0.91 | RAD52 (0.69) | RAD52POLBRXFP1FLT3TERT | |
| Hydrochloric Acid SCHEMBL4509102 | 0.83 | RAD52 (0.69) | RAD52POLBRXFP1FLT3TERT | |
| SCHEMBL1289489 | 0.79 | ALDH1A1 (0.65) | RAD52POLBRXFP1FLT3TERT | |
| Hydrochloric Acid SCHEMBL4502066 | 0.78 | ALDH1A1 (0.67) | RAD52POLBRXFP1FLT3TERT | |
| SCHEMBL1687915 | 0.78 | RAD52 (0.72) | RAD52POLBRXFP1FLT3TERT | |
| SCHEMBL12473328 | 0.77 | KMT2A (0.42) | FLT3CNR2GSK3BLMNACYP1A2 | |
| SCHEMBL1289455 | 0.77 | RAD52 (0.59) | RAD52POLBRXFP1FLT3TERT | |
| SCHEMBL1289391 | 0.77 | RAD52 (0.59) | RAD52POLBRXFP1FLT3TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046207-A1 | ANTI-PARASITIC SUBSTITUTED RING FUSED AZINE COMPOUNDS | PARACO TECHNOLOGY LIMITED (NZ) | 2012-04-12 | — | — | WO | disclosed |