Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16311864 | 0.95 | ATM (0.43) | ATML3MBTL1PPARGMAPTKCNH2 | |
| SCHEMBL7096253 | 0.94 | ATM (0.49) | ATML3MBTL1PPARGMAPTKCNH2 | |
| SCHEMBL625611 | 0.93 | MMP14 (0.49) | ATML3MBTL1PPARGMAPTKCNH2 | |
| SCHEMBL9655690 | 0.93 | PPARG (0.46) | ATML3MBTL1PPARGMAPTMEN1 | |
| SCHEMBL625610 | 0.93 | MMP14 (0.49) | ATML3MBTL1PPARGMAPTKCNH2 | |
| SCHEMBL8614034 | 0.90 | LSS (0.43) | ATML3MBTL1PPARGMAPTKCNH2 | |
| SCHEMBL9313658 | 0.88 | ACHE (0.47) | L3MBTL1MAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL9551059 | 0.88 | MAPT (0.52) | ATML3MBTL1MAPTKCNH2MAPK1 | |
| SCHEMBL2602717 | 0.87 | MMP14 (0.47) | ATML3MBTL1MAPTMAPK1MEN1 | |
| SCHEMBL6932967 | 0.87 | MMP14 (0.47) | ATML3MBTL1MAPTMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329842-B2 | Ophthalmological composition and use thereof | Arcltec GmbH (DE) | 2012-12-11 | — | — | US | disclosed |
| US-8329842-B2 | Ophthalmological composition and use thereof | Arcltec GmbH (DE) | 2012-12-11 | — | — | US | disclosed |
| US-20110028667-A1 | Copolymer and Ophthalmological Composition | *ACRI.TEC GMBH (DE) | 2011-02-03 | — | — | US | disclosed |
| US-20110028667-A1 | Copolymer and Ophthalmological Composition | *ACRI.TEC GMBH (DE) | 2011-02-03 | — | — | US | disclosed |
| US-20100324165-A1 | Ophthalmological Composition And Use Thereof | CARL ZEISS MEDITEC AG (DE) | 2010-12-23 | — | — | US | disclosed |
| US-20100324165-A1 | Ophthalmological Composition And Use Thereof | CARL ZEISS MEDITEC AG (DE) | 2010-12-23 | — | — | US | disclosed |