Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 2/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12895484 | 0.88 | ATM (0.46) | ALDH1A1LMNAKMT2AMAPK1MEN1 | |
| SCHEMBL9312727 | 0.87 | CRHBP (0.46) | CRHBPCRHR2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7096253 | 0.85 | ATM (0.49) | ALDH1A1LMNAKMT2AMAPK1MEN1 | |
| SCHEMBL9312191 | 0.84 | FAAH (0.45) | ACHECRHBPCRHR2ALDH1A1LMNA | |
| SCHEMBL16311864 | 0.84 | ATM (0.43) | ACHEARALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9655690 | 0.82 | PPARG (0.46) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8614034 | 0.82 | LSS (0.43) | ALDH1A1LMNAKMT2AMAPK1MEN1 | |
| SCHEMBL625611 | 0.82 | MMP14 (0.49) | ALDH1A1SMN1; SMN2KMT2AMAPK1TDP1 | |
| SCHEMBL625610 | 0.82 | MMP14 (0.49) | ALDH1A1SMN1; SMN2KMT2AMAPK1TDP1 | |
| SCHEMBL9551059 | 0.80 | MAPT (0.52) | CRHBPCRHR2ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5334710-A | Monomeric or polymeric compounds | SANDOZ LTD. (CH) | 1994-08-02 | — | — | US | disclosed |