SCHEMBL128961

SCHEMBL128961

C#CCCCCCCCCCCC[CH2]

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
MAPT P10636 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CYP3A4 P08684 2/20 0.39
ALDH1A1 P00352 2/20 0.39
ALOX15 P16050 1/20 0.39
USP2 O75604 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
KDM4E B2RXH2 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL128669 1.00 CYP1A2 (0.44) CYP1A2CYP2D6MAPTCYP2C9CYP2C19
SCHEMBL128196 1.00
SCHEMBL1274555 1.00 CYP1A2 (0.44) CYP1A2CYP2D6MAPTCYP2C9CYP2C19
SCHEMBL1275460 1.00 CYP1A2 (0.44) CYP1A2CYP2D6MAPTCYP2C9CYP2C19
SCHEMBL128011 1.00 CYP1A2 (0.44) CYP1A2CYP2D6MAPTCYP2C9CYP2C19
SCHEMBL141691 1.00 CYP1A2 (0.44) CYP1A2CYP2D6MAPTCYP2C9CYP2C19
SCHEMBL1228396 1.00 CYP1A2 (0.44) CYP1A2CYP2D6MAPTCYP2C9CYP2C19
SCHEMBL20503206 1.00 CYP1A2 (0.44) CYP1A2CYP2D6MAPTCYP2C9CYP2C19
SCHEMBL20503190 1.00 CYP1A2 (0.44) CYP1A2CYP2D6MAPTCYP2C9CYP2C19
SCHEMBL126569 1.00 CYP1A2 (0.44) CYP1A2CYP2D6MAPTCYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11732244-B2 Methods for increasing the infectivity of viruses utilizing alkyne-modified fatty acids THE JOHNS HOPKINS UNIVERSITY (US) 2023-08-22 US claimed
US-10808228-B2 Methods for increasing the infectivity of viruses utilizing alkyne-modified fatty acids THE JOHNS HOPKINS UNIVERSITY (US) 2020-10-20 US claimed
US-20180201907-A1 METHODS FOR INCREASING THE INFECTIVITY OF VIRUSES Life Technologies Corporation 2018-07-19 US claimed
US-20180171306-A1 METHODS FOR INCREASING THE INFECTIVITY OF VIRUSES Life Technologies Corporation 2018-06-21 US claimed
EP-2807252-B1 METHODS FOR INCREASING THE INFECTIVITY OF VIRUSES LIFE TECHNOLOGIES CORP (US) 2017-05-10 EP claimed
US-20150037288-A1 METHODS FOR INCREASING THE INFECTIVITY OF VIRUSES Life Technologies Corporation 2015-02-05 US claimed
CN-104245925-A Methods for increasing viral infectivity LIFE TECHNOLOGIES CORP 2014-12-24 CN claimed
CN-104220588-A Methods for increasing viral infectivity LIFE TECHNOLOGIES CORP 2014-12-17 CN claimed
EP-2807251-A1 METHODS FOR INCREASING THE INFECTIVITY OF VIRUSES Life Technologies Corporation (US) 2014-12-03 EP claimed
EP-2807252-A1 METHODS FOR INCREASING THE INFECTIVITY OF VIRUSES Life Technologies Corporation (US) 2014-12-03 EP claimed
WO-2013112778-A1 METHODS FOR INCREASING THE INFECTIVITY OF VIRUSES Life Technologies Corporation (US) 2013-08-01 WO claimed
WO-2013112780-A1 METHODS FOR INCREASING THE INFECTIVITY OF VIRUSES Life Technologies Corporation (US) 2013-08-01 WO claimed
US-20240218254-A1 ADDITIVE FOR SURFACE ACTIVATION, AND EMULSION COMPOSITION USING SAME MIYOSHI OIL & FAT CO., LTD. (JP) 2024-07-04 US disclosed
EP-4327889-A1 FORMULATION USING AMINO ACID AND CARBOXYLIC ACID, ORGANIC SALT, AND COMPOSITION COMPRISING SAME AND USE THEREOF Miyoshi Oil & Fat Co., Ltd. (JP) 2024-02-28 EP disclosed
CN-117203302-A Complexes, organic salts and compositions containing them and uses thereof 三吉油脂株式会社 2023-12-08 CN disclosed
US-20230340356-A1 ADDITIVE OR COMPOSITION FOR IMPARTING LUBRICITY MIYOSHI OIL & FAT CO., LTD. (JP) 2023-10-26 US disclosed
EP-1015427-A1 SUBSTITUTED 2-PYRROLIDINONE ACTIVATORS OF PKC GEORGETOWN UNIVERSITY (US) 2000-07-05 EP disclosed
EP-0983768-A1 MEDICINAL COMPOSITION FOR PREVENTION OR TREATMENT OF HEPATOPATHY Nippon Shinyaku Co., Ltd. (JP) 2000-03-08 EP disclosed
US-5962504-A ACTIVATOR OF PROTEIN KINASE; ANTICANCER AGENT GEORGETOWN UNIVERSITY (US) 1999-10-05 US disclosed
WO-1999012901-A1 SUBSTITUTED 2-PYRROLIDINONE ACTIVATORS OF PKC GEORGETOWN UNIVERSITY (US) 1999-03-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11732244-B2 Methods for increasing the infectivity of viruses utilizing alkyne-modified fatty acids LIPA, NPC1L1, LIPC CYP1A2 2507/4885CYP2D6 2475/4885MAPT 2713/4885
US-20150037288-A1 METHODS FOR INCREASING THE INFECTIVITY OF VIRUSES LIPA, NPC1L1, LIPC CYP1A2 2283/4885CYP2D6 2287/4885MAPT 2589/4885
US-20180201907-A1 METHODS FOR INCREASING THE INFECTIVITY OF VIRUSES LIPA, NPC1L1, LIPC CYP1A2 2283/4885CYP2D6 2287/4885MAPT 2589/4885
US-10808228-B2 Methods for increasing the infectivity of viruses utilizing alkyne-modified fatty acids LIPA, NPC1L1, LIPC CYP1A2 2507/4885CYP2D6 2475/4885MAPT 2713/4885
US-20180171306-A1 METHODS FOR INCREASING THE INFECTIVITY OF VIRUSES LIPA, NPC1L1, LIPC CYP1A2 2283/4885CYP2D6 2287/4885MAPT 2589/4885
US-20240218254-A1 ADDITIVE FOR SURFACE ACTIVATION, AND EMULSION COMPOSITION USING SAME HAO2, NOTUM, FFAR2 CYP1A2 1218/4885CYP2D6 1885/4885MAPT 4421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.