Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 2/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29935898 | 1.00 | KDM4E (0.42) | KDM4EALDH1A1SMN1; SMN2LMNAERN1 | |
| Hydrochloric Acid SCHEMBL28102148 | 0.98 | KDM4E (0.41) | KDM4EALDH1A1SMN1; SMN2LMNAERN1 | |
| SCHEMBL27839547 | 0.83 | PTGER4 (0.33) | KDM4EALDH1A1SMN1; SMN2LMNAPDGFRB | |
| SCHEMBL2006927 | 0.81 | ALDH1A1 (0.39) | KDM4EALDH1A1SMN1; SMN2PDGFRBPDGFRA | |
| SCHEMBL274826 | 0.75 | ALDH1A1 (0.44) | KDM4EALDH1A1SMN1; SMN2CYP2A6RAB9A | |
| SCHEMBL97820 | 0.75 | RAB9A (0.49) | KDM4EALDH1A1SMN1; SMN2LMNARAB9A | |
| SCHEMBL13749555 | 0.75 | PDGFRB (0.40) | KDM4EALDH1A1SMN1; SMN2PDGFRBPDGFRA | |
| SCHEMBL232458 | 0.74 | PDGFRB (0.65) | KDM4EALDH1A1SMN1; SMN2LMNAPDGFRB | |
| SCHEMBL29269457 | 0.74 | PDE10A (0.33) | KDM4EALDH1A1ERN1MAPTATAD2 | |
| SCHEMBL31003026 | 0.74 | PDE10A (0.33) | KDM4EALDH1A1ERN1MAPTATAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164458-A | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2021-07-23 | — | — | CN | claimed |
| CN-109223779-B | Pharmaceutical composition for promoting fracture healing and preparation method and application thereof | 山东中医药大学 | 2020-07-17 | — | — | CN | claimed |
| CN-109223779-A | A kind of pharmaceutical composition and its preparation method and application promoting union | 苏涛 | 2019-01-18 | — | — | CN | claimed |
| CN-104151316-B | Tricyclazole alkanone Antibiotique composition | 埃科特莱茵药品有限公司 | 2016-06-15 | — | — | CN | claimed |
| CN-104903322-A | Antibacterial oxadiazolone derivatives | ACTELION PHARMACEUTICALS LTD | 2015-09-09 | — | — | CN | claimed |
| CN-104151316-A | Tricyclic oxazolidinone antibiotic compounds | ACTELION PHARMACEUTICALS LTD | 2014-11-19 | — | — | CN | claimed |
| CN-103958525-A | 3,7-disubstituted octahydro-2h-pyrido[4,3-e][1,3]oxazin-2-one antibiotics | ACTELION PHARMACEUTICALS LTD | 2014-07-30 | — | — | CN | claimed |
| CN-103265559-A | Substituted tricyclic benzoquinone compound and preparation method and application thereof | UNIV PLA 2ND MILITARY MEDICAL | 2013-08-28 | — | — | CN | claimed |
| CN-103254191-A | Substituted aryl tetracyclic antifungal compound as well as preparation method and application thereof | UNIV PLA 2ND MILITARY MEDICAL | 2013-08-21 | — | — | CN | claimed |
| CN-102015710-B | Azatricyclic antibiotic compounds | ACTELION PHARMACEUTICALS LTD | 2013-04-24 | — | — | CN | claimed |
| CN-102164925-A | Tricyclic oxazolidinone antibiotic compounds | ACTELION PHARMACEUTICALS LTD | 2011-08-24 | — | — | CN | claimed |
| CN-1297556-C | New benzo[b]chromeno-naphthyridin-7-one and pyrano[2',3':7,8] quino[2,3-b]quinoxalin-7-one compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2007-01-31 | — | — | CN | claimed |
| CN-1680372-A | New benzo[b]chromeno-naphthyridin-7-one and pyrano[2',3':7,8] quino[2,3-b]quinoxalin-7-one compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2005-10-12 | — | — | CN | claimed |
| EP-3894401-A2 | NAPHTHYRIDINE AND QUINOLINE DERIVATIVES USEFUL AS ALK5 INHIBITORS | Theravance Biopharma R&D IP, LLC (US) | 2021-10-20 | — | — | EP | disclosed |
| CN-113164458-A | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2021-07-23 | — | — | CN | disclosed |
| WO-2020123453-A2 | ALK5 INHIBITORS | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2020-06-18 | — | — | WO | disclosed |
| CN-1420890-A | Tricyclic imidazopyridines | OTANNER PHARMA AG (DE) | 2003-05-28 | — | — | CN | disclosed |
| CN-1039010-C | Novel 3-oxadiazolyl-1,6-naphthyridine derivatives | DAINIPPON PHARMACEUTICAL CO (JP) | 1998-07-08 | — | — | CN | disclosed |
| WO-1998006709-A1 | CYCLIC UREA COMPOUNDS, THEIR PRODUCTION AND USE AS HERBICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-19 | — | — | WO | disclosed |
| CN-1086517-A | Novel 3-oxadiazole base-1, the 6-naphthyridines derivatives | DAINIPPON PHARMACEUTICAL CO (JP) | 1994-05-11 | — | — | CN | disclosed |