Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.49 |
| ▸ | CLK1 | P49759 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.49 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.49 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29985017 | 0.86 | RAB9A (0.40) | RAB9ANPC1PIK3CDCSNK2A2MAOB | |
| SCHEMBL29984441 | 0.83 | ALDH1A1 (0.39) | RAB9ANPC1PIK3CDCSNK2A2MAOB | |
| SCHEMBL30837162 | 0.79 | CYP3A4 (0.49) | RAB9ANPC1PIK3CDCSNK2A2MAOB | |
| SCHEMBL6655659 | 0.79 | CYP3A4 (0.49) | RAB9ANPC1PIK3CDCSNK2A2MAOB | |
| SCHEMBL6655669 | 0.79 | CYP3A4 (0.49) | RAB9ANPC1PIK3CDCSNK2A2MAOB | |
| SCHEMBL3390677 | 0.79 | TRIM24 (0.50) | RAB9ANPC1DYRK1ADYRK2DYRK1B | |
| SCHEMBL19792523 | 0.79 | NPC1 (0.46) | RAB9ANPC1PIK3CDCSNK2A2MAOB | |
| SCHEMBL28255393 | 0.78 | MAPT (0.44) | RAB9ANPC1PIK3CDCSNK2A2MAOB | |
| SCHEMBL3274768 | 0.77 | NPC1 (0.45) | RAB9ANPC1PIK3CDCSNK2A2MAOB | |
| SCHEMBL28254402 | 0.77 | NPC1 (0.45) | RAB9ANPC1PIK3CDCSNK2A2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 501 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164458-B | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2024-09-13 | — | — | CN | claimed |
| CN-116082411-A | Ir (III) complex with antitumor immune activity and preparation method and application thereof | 广东医科大学 | 2023-05-09 | — | — | CN | claimed |
| US-11597728-B2 | Monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-03-07 | — | — | US | claimed |
| EP-3856179-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | Janssen Pharmaceutica N.V. (BE) | 2021-08-04 | — | — | EP | claimed |
| CN-113164458-A | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2021-07-23 | — | — | CN | claimed |
| CN-113164459-A | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2021-07-23 | — | — | CN | claimed |
| CN-113121541-A | Synthesis and application of fluorescent probe capable of distinguishing gold ions and palladium species simultaneously | 湖南师范大学 | 2021-07-16 | — | — | CN | claimed |
| WO-2020065614-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | claimed |
| US-20200102311-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | US | claimed |
| CN-104080455-B | Certain chemical entities, compositions, and methods | 润新生物公司 | 2018-07-31 | — | — | CN | claimed |
| CN-104053442-B | Certain chemical entities, compositions, and methods | 润新生物公司 | 2017-06-23 | — | — | CN | claimed |
| CN-103224470-A | Preparation method and application of quinoxaline-6-phenylhydrazone derivants | UNIV NANJING AGRICULTURAL | 2013-07-31 | — | — | CN | claimed |
| US-20120116027-A1 | PROCESS FOR THE PURIFICATION OF HUMAN GROWTH HORMONE POLYPEPTIDES USING AFFINITY RESINS COMPRISING SPECIFIC LIGANDS | NOVO NORDISK A/S (DK) | 2012-05-10 | — | — | US | claimed |
| CN-102216325-A | Method for purifying human growth hormone polypeptides using affinity resins comprising specific ligands | NOVO NORDISK AS | 2011-10-12 | — | — | CN | claimed |
| EP-2356141-A1 | PROCESS FOR THE PURIFICATION OF HUMAN GROWTH HORMONE POLYPEPTIDES USING AFFINITY RESINS COMPRISING SPECIFIC LIGANDS | Novo Nordisk A/S (DK) | 2011-08-17 | — | — | EP | claimed |
| WO-2010055135-A1 | PROCESS FOR THE PURIFICATION OF HUMAN GROWTH HORMONE POLYPEPTIDES USING AFFINITY RESINS COMPRISING SPECIFIC LIGANDS | NOVO NORDISK A/S (DK) | 2010-05-20 | — | — | WO | claimed |
| US-4413999-A | CHROMATOGRAPHY, BIOCHEMICAL IMMOBILIZATION, FIBER REACTIVE DYES | RESEARCH PRODUCTS REHOVOT LTD. (IL) | 1983-11-08 | — | — | US | claimed |
| EP-4727932-A1 | SMALL MOLECULE LIGANDS AND APTAMERS | MeiraGTx Gene Regulation Limited (GB) | 2026-04-22 | — | — | EP | disclosed |
| EP-0135630-A1 | Amidoxime derivatives, processes for the preparation thereof and uses therefor | RESEARCH PRODUCTS REHOVOT LTD. (IL) | 1985-04-03 | — | — | EP | disclosed |
| US-4413999-A | CHROMATOGRAPHY, BIOCHEMICAL IMMOBILIZATION, FIBER REACTIVE DYES | RESEARCH PRODUCTS REHOVOT LTD. (IL) | 1983-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120116027-A1 | PROCESS FOR THE PURIFICATION OF HUMAN GROWTH HORMONE POLYPEPTIDES USING AFFINITY RESINS COMPRISING SPECIFIC LIGANDS | GHRHR, GHITM, GHSR | RAB9A 4091/4885NPC1 4653/4885PIK3CD 4498/4885 |
| US-20200102311-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | RAB9A 994/4885NPC1 826/4885PIK3CD 855/4885 |
| US-11597728-B2 | Monoacylglycerol lipase modulators | MGLL, LPL, PNLIP | RAB9A 994/4885NPC1 826/4885PIK3CD 855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.