Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 15/20 | 0.54 |
| ▸ | CTSK | P43235 | 14/20 | 0.54 |
| ▸ | CTSL | P07711 | 5/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21266462 | 1.00 | CTSS (0.54) | CTSSCTSKCTSLCTSBDPP4 | |
| SCHEMBL12884397 | 0.82 | CTSS (0.53) | CTSSCTSKCTSLCTSB | |
| SCHEMBL19135317 | 0.78 | — | — | |
| SCHEMBL14108236 | 0.78 | USP2 (0.46) | CTSSCTSKDPP4 | |
| SCHEMBL9967749 | 0.78 | — | — | |
| SCHEMBL13688963 | 0.77 | ALDH1A1 (0.57) | — | |
| SCHEMBL9963457 | 0.76 | TSHR (0.37) | CTSSCTSKDPP4 | |
| SCHEMBL13821899 | 0.76 | TSHR (0.37) | CTSSCTSKDPP4 | |
| SCHEMBL13575676 | 0.76 | TSHR (0.37) | CTSSCTSKDPP4 | |
| SCHEMBL11336790 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028447-A1 | INDAZOLE DERIVATIVES | PFIZER INC. | 2011-02-03 | — | — | US | disclosed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028447-A1 | INDAZOLE DERIVATIVES | CNR1, CNR2, GPR119 | CTSS 2697/4885CTSK 2324/4885CTSL 4060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.