Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.46 |
| ▸ | PRCP | P42785 | 1/20 | 0.45 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12929857 | 1.00 | NAAA (0.46) | NAAAEPHX1PRCPGNAI3GNAO1 | |
| SCHEMBL5545047 | 0.83 | TRPV1 (0.42) | — | |
| SCHEMBL5538106 | 0.83 | TRPV1 (0.42) | — | |
| SCHEMBL30925003 | 0.81 | TLR4 (0.43) | NAAAEPHX1PRCP | |
| SCHEMBL14262594 | 0.74 | AHCY (0.45) | EPHX1 | |
| SCHEMBL20161710 | 0.74 | FUCA1 (0.47) | EPHX1 | |
| SCHEMBL18214282 | 0.73 | NAAA (0.41) | NAAAEPHX1PRCPGNAI3GNAO1 | |
| SCHEMBL20161683 | 0.73 | MMP8 (0.42) | NAAAEPHX1GNAI3GNAO1GNAI1 | |
| SCHEMBL20161420 | 0.73 | MMP8 (0.42) | NAAAEPHX1GNAI3GNAO1GNAI1 | |
| SCHEMBL18214274 | 0.73 | NAAA (0.41) | NAAAEPHX1PRCPGNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7884202-B2 | Nucleobases are perfluoroalkylated in a one step process with a perfluoroalkyl halide in the presence of a sulfoxide, a peroxide and an iron compound; useful as medicinal drugs, intermediates for medicinal drugs and agricultural chemicals | TOSOH CORPORATION (JP) | 2011-02-08 | — | — | US | disclosed |