Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.55 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.55 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.53 |
| ▸ | AR | P10275 | 6/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30963689 | 1.00 | TRIM24 (0.55) | TRIM24TRIM33BRPF1ARHTR2A | |
| SCHEMBL2143637 | 0.80 | TRIM24 (0.60) | TRIM24TRIM33BRPF1ARHTR2A | |
| SCHEMBL31607554 | 0.80 | TRIM24 (0.60) | TRIM24TRIM33BRPF1ARHTR2A | |
| SCHEMBL31302783 | 0.75 | TRIM24 (0.55) | TRIM24TRIM33BRPF1ARHTR2A | |
| SCHEMBL19518384 | 0.75 | TRIM24 (0.55) | TRIM24TRIM33BRPF1ARHTR2A | |
| SCHEMBL21623871 | 0.75 | BRPF1 (0.58) | TRIM24TRIM33BRPF1ARHTR2A | |
| SCHEMBL17150712 | 0.75 | TRIM24 (0.55) | TRIM24TRIM33BRPF1ARHTR2A | |
| SCHEMBL12865280 | 0.75 | TRIM24 (0.55) | TRIM24TRIM33BRPF1ARHTR2A | |
| SCHEMBL31049280 | 0.75 | HTR2A (0.56) | TRIM24TRIM33BRPF1ARHTR2A | |
| SCHEMBL23658612 | 0.75 | GPR84 (0.58) | DYRK1AAXLPCSK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028463-A1 | AMIDE COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028463-A1 | AMIDE COMPOUNDS | PTGER4, PTGER1, PTGER2 | TRIM24 3869/4885TRIM33 4121/4885BRPF1 883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.